Results 191 to 200 of about 2,473,933 (318)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The location model with two periods of price competition

Game Theory;Location Theory;Nash Equilibrium;Price ...
Webers, H.M.
core  

Informational Content of the VIX Index: Dynamic Entropy Approach. [PDF]

Entropy (Basel)
Olbryś J, Toczydłowski D.
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

A computational case study of Günter Blobel's idea of protein topogenesis and its influence. [PDF]

Hist Philos Life Sci
Jinson ST, Maienschein J, Laubichler M.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Effects of seasonality and different rearing systems on the behavior and thermal comfort of sheep in the northern region of Brazil, eastern Amazon. [PDF]

Front Vet Sci
de Andrade RL, de Holanda RS, Sousa CEL, da Silva TN, Vilela LGP, de Carvalho KC, Belo TS, de Oliveira ES, Ribeiro WKM, Bruxel RRSR, Campinas BS, Barreto LB, da Silva RUNC, de Alencar JS, Martorano LG, de Araújo CV, Camargo-Júnior RNC, da Silva ÉBR, Pinto VS, de Souza IMF, da Silva WC.   +20 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Lexikon der Byzantinischen Gräzität, besonders des 9. —12. Jahrhunderts. 1. Fasz. (a aQyvQO^topiov).

, 2021
A. , Periods
core  

Analyzing Trends in the Incidence of Trauma and Mechanisms of Injury Before, During, and After COVID-19 Lockdown in a Staten Island Level 1 Trauma Center. [PDF]

Cureus
Bogdanovski DA, Rubinshteyn V, Harrington T, LeBaron J, Cohen D, Issack PS, Basu A.   +6 more
europepmc   +1 more source