Results 71 to 80 of about 697,428 (396)

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A., Buscemi R., Karch S. B., Lanzarone A., Roccuzzo R., Zerbo S.   +5 more
core   +1 more source

Agreement of administrative pharmacy dispensing with self‐reported use of oral prednisone in US Veterans with rheumatoid arthritis

Arthritis Care &Research, Accepted Article.
Objective Administrative claims are used to evaluate oral glucocorticoid use in rheumatoid arthritis (RA), despite limited evidence to support accuracy. We aimed to evaluate the performance of claims‐based algorithms for glucocorticoid use compared to self‐report in an RA population.
Beth I. Wallace, Bryant R. England, Joshua F. Baker, Michael D. George, Brian C. Sauer, Jorge Rojas, Punyasha Roul, Katherine D. Wysham, Hannah Brubeck, Isaac Smith, Liron Caplan, Paul A. Monach, Gail S. Kerr, Gary Kunkel, Tawnie Braaten, Ted R. Mikuls, Grant W. Cannon   +16 more
wiley   +1 more source

Primer on adult patient satisfaction in perioperative settings. [PDF]

, 2019
The topic of patient satisfaction has gained increasing importance over the past decade. Due to the impact of patient satisfaction on health care quality, understanding factors that predict satisfaction is vital.
Fortier, Michelle A, Kain, Zeev N, Trinh, Lily N   +2 more
core  

Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively : a case control study [PDF]

, 2012
Introduction: Acute kidney injury (AKI) after cardiac surgery increases length of hospital stay and in-hospital mortality. A significant number of patients undergoing cardiac surgical procedures require perioperative intra-aortic balloon pump (IABP ...
Bingold, Tobias Michael, Eltzschig, Holger K., Lawlor, Garrett, Mitani, Aya, Nowak-Machen, Martina, Rawn, James D., Rosenberger, Peter, Shekar, Prem S., Shernan, Stanton K., Tuli, Sagun   +9 more
core   +2 more sources

Neuroinflammation and Perioperative Neurocognitive Disorders

Anesthesia and Analgesia, 2019
Neuroinflammation has become a key hallmark of neurological complications including perioperative pathologies such as postoperative delirium and longer-lasting postoperative cognitive dysfunction.
Saraswathi Subramaniyan, N. Terrando
semanticscholar   +1 more source

Perioperatives Wärmemanagement

Der Anaesthesist, 2006
Perioperative hypothermia can influence clinical outcome negatively. It triples the incidence of adverse myocardial outcomes, significantly increases perioperative blood loss, significantly augments allogenic transfusion requirements, and increases the incidence of surgical wound infections.
Braeuer, Anselm, Perl, Tal Naggan, Quintel, M.   +2 more
openaire   +4 more sources

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman, Graham F. Barber, S'Dravious A. DeVeaux, Edward A. Botchwey, Daniel Refai, Adam M. Klein, Andrés J. García   +6 more
wiley   +1 more source

Suppression of the postoperative neutrophil leucocytosis following neoadjuvant chemoradiotherapy for rectal cancer and implications for surgical morbidity [PDF]

, 2010
Objective: The extent to which neoadjuvant chemoradio- therapy for rectal cancer influences postoperative morbid- ity is controversial. This study investigated whether this treatment suppresses the normal perioperative inflamma- tory response and ...
Anonymous, Artioukh, Bosset, Buie, Bujko, Bullard, Cohen, Gerard, Goldberg, Hartley, Kerr, Marijnen, Pahlman, Royal College of Pathologists Working Group on Cancer Services, Sauer, Wichmann, Wong   +16 more
core   +1 more source

Perioperative Opioid Administration.

Anesthesiology, 2020
Opioids form an important component of general anesthesia and perioperative analgesia. Discharge opioid prescriptions are identified as a contributor for persistent opioid use and diversion.
H. Shanthanna, K. Ladha, H. Kehlet, G. Joshi   +3 more
semanticscholar   +1 more source