Results 101 to 110 of about 158,366 (318)

Dynamic Predictions of Postoperative Complications from Explainable, Uncertainty-Aware, and Multi-Task Deep Neural Networks [PDF]

arXiv, 2020
Accurate prediction of postoperative complications can inform shared decisions regarding prognosis, preoperative risk-reduction, and postoperative resource use. We hypothesized that multi-task deep learning models would outperform random forest models in predicting postoperative complications, and that integrating high-resolution intraoperative ...
arxiv  

Combined effect of frailty and sarcopenia on postoperative complications in older adults undergoing curative surgery for hepato‐biliary‐pancreatic cancer

Annals of Gastroenterological Surgery, EarlyView.
A multivariable logistic regression model was performed using covariates that were significant in the bivariable analyses, including bile duct cancer, longer operative times, and greater blood loss. Prefrail or frail status combined with sarcopenia remained significant in this model (OR 4.74; 95% CI, 1.10–20.29; p = 0.04).
Norifumi Harimoto, Keishi Sugimachi, Tomohiro F. Nishijima, Tomino Takahiro, Tomonari Shimagaki, Yohei Mano, Emi Onishi, Masahiko Sugiyama, Yasue Kimura, Masaru Morita   +9 more
wiley   +1 more source

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

Cell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner, Neda Dadgar, Anil Vaidya, Robert Simon, Clifton Fulmer, Hassan Siddiki, K. V. Narayanan Menon, Peter Liu, R. Matthew Walsh   +8 more
wiley   +1 more source

Macro- and microscopic changes in veins with short-term central venous catheters: an observational autopsy study

BMC Anesthesiology
Background Centrally inserted central catheters (CICCs) are indispensable in modern healthcare, but unfortunately, come with complications. Catheter-related thrombosis is a well-known complication reported to occur in 5–30% of patients with CICC.
Mika M. Rockholt, Leila Naddi, Ahmed M. Badri, Elisabet Englund, Thomas Kander   +4 more
doaj   +1 more source

Risk factors for pneumonia after endoscopic laryngopharyngeal surgery in cases with prior esophageal cancer treatment

Annals of Gastroenterological Surgery, EarlyView.
This study found that the risk factors for postoperative pneumonia after endoscopic laryngopharyngeal surgery for superficial laryngopharyngeal cancer were multiple lesions and larger lesion diameter. Prior esophagectomy for esophageal cancer did not increase the incidence of pneumonia, suggesting the procedure can be safely performed with careful ...
Atsushi Nakao, Hirofumi Kawakubo, Masashi Takeuchi, Satoru Matsuda, Kazumasa Fukuda, Yuko Kitagawa   +5 more
wiley   +1 more source

Coronary angiography of the ex‐situ beating donor heart in a portable organ care system

Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1252-1260, December 1, 2022., 2022
Abstract Objectives To determine safety and feasibility of ex‐situ coronary angiography. Background To cater for the perpetually growing demand for heart donors, interest in donation following circulatory death (DCD) has been rekindled. Further pursuit of donor pool expansion has led to eligibility extension to “marginal” donors who are at higher risk ...
Thomas Meredith, Sarah Scheuer, Michael Hoffman, Yashutosh Joshi, Krishna Kathir, Brendan Gunalingam, David Roy, Stephanie Wilson, Paul Jansz, Peter Macdonald, David Muller   +10 more
wiley   +1 more source

The anesthetic management of a child with ohtahara syndrome and severe stridor: a case report

BMC Pediatrics
Background Ohtahara syndrome is a progressive developmental and epileptic encephalopathy that manifests in the early infantile period. This rare condition is characterized by intractable seizures, psychomotor retardation, and poor prognosis.
Nidhi Patel, Peymon Madi, Iona Monteiro, Shridevi Pandya Shah   +3 more
doaj   +1 more source

Reduction of breast cancer relapses with perioperative non-steroidal anti-inflammatory drugs: new findings and a review [PDF]

arXiv, 2013
To explain a bimodal pattern of hazard of relapse among early stage breast cancer patients identified in multiple databases, we proposed that late relapses result from steady stochastic progressions from single dormant malignant cells to avascular micrometastases and then on to growing deposits.
arxiv  

Analysis of the characteristics and management of perforated peptic ulcer from 2011 to 2022: A multicenter and retrospective descriptive study

Annals of Gastroenterological Surgery, EarlyView.
The in‐hospital mortality rate for perforated peptic ulcer in this study was 5.0%, and conservative treatment was safely performed even in elderly patients. As the perforation diameter increased, the rate of gastrectomy tended to rise, and the rate of anastomotic leakage in those patients was high.
Hiromasa Hoshi, Akira Endo, Koji Ito, Tomohiro Akutsu, Hikaru Odera, Hideto Shiraki, Kei Ito, Takeshi Yokoyama, Yasukazu Narita, Taro Masuda, Akira Suekane, Koji Morishita   +11 more
wiley   +1 more source

How to Assess the Impact of Quality and Patient Safety Interventions with Routinely Collected Longitudinal Data [PDF]

arXiv, 2018
Measuring the effect of patient safety improvement efforts is needed to determine their value but is difficult due to the inherent complexities of hospital operations. In this paper, we show by case study how interrupted time series design can be used to isolate and measure the impact of interventions while accounting for confounders often present in ...
arxiv