Results 71 to 80 of about 3,766,251 (261)

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

A comparative study of perioperative outcomes in open radical cystectomy, laparoscopic radical cystectomy, and robotic-assisted radical cystectomy

Urology Annals
Introduction: Radical cystectomy (RC) is the standard treatment for muscle-invasive and high-risk nonmuscle-invasive bladder cancer. The impact of minimally invasive surgeries (MIS) such as laparoscopic and robot-assisted RC (RARC) on outcomes and ...
Vishal Narkhede, Siddhant Bolar, Deepanshu Aggarwal, Rudra Prasad Ghorai, Sidhartha Kalra, Lalgudi Narayanan Dorairajan, Sreerag Kodakkattil Sreenivasan   +6 more
doaj   +1 more source

The effects of staffing practices on safety and quality of perioperative nursing care – an integrative review

, 2021
Patients undergoing invasive procedures are highly vulnerable to adverse outcomes. From 2012 to 2013, 5.5 per cent of all inpatient admissions reported an adverse event.
Nick Nijkamp, Paula Foran (13790950), Paula Foran, Nick Nijkamp (9822956)   +3 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Association of conduit dimensions with perioperative outcomes and long-term quality of life after esophagectomy for malignancyCentral MessagePerspective

JTCVS Open
Objective: The impact of conduit dimensions and location of esophagogastric anastomosis on long-term quality of life after esophagectomy remains unexplored.
SangMin Kim, MD, Sun Yeop Lee, MS, Nuno Vaz, MD, Rachel Leo, BA, Rafael R. Barcelos, MD, Rena Mototani, BA, Antonio Lozano, BA, Evert Andrew Sugarbaker, BS, Sarah S. Oh, PhD, Francine Jacobson, MD, Jon O. Wee, MD, Michael T. Jaklitsch, MD, M. Blair Marshall, MD   +12 more
doaj   +1 more source

Liquid‐Responsive Shape‐Memory Nanofiber‐Reinforced Scaffolds for Cartilage Repair

Advanced Science, EarlyView.
A liquid‐responsive shape‐memory, nanofiber‐reinforced QCG scaffold combines conformal defect filling, an aligned architecture that is structurally permissive for endogenous cell infiltration, and sustained KGN release. This integrated design enhances BMSC viability, migratory activity, and chondrogenic differentiation and promotes hyaline cartilage ...
Jiyang Zeng, Wei Li, Yawei Li, Zhiming Tu, Hong Ma, Yuliang Dai, Zhaoling Ma, Tao Yuan, Bing Wang   +8 more
wiley   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Precision Medicine in Anesthesia: Pharmacogenomics and Personalized Care

National Board of Examinations Journal of Medical Sciences
Precision medicine in anesthesia represents a transformative approach aimed at optimizing anesthetic care by tailoring interventions to individual patient characteristics, particularly their genetic profile.
Amit Kumar Malviya, Puneet Khanna
doaj   +1 more source

Surgical outcomes and patient-centred perioperative programs

, 2023
Perioperative medicine is changing, and its goals are expanding. More and more attention is paid to the surgical experience and the patient's quality of life. Patient-reported data represent a useful tool in this context.
Celoria S., Bignami E., Bellini V.
core   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source