Results 81 to 90 of about 3,766,251 (261)

Current and emerging treatments for hypercholesterolemia: A focus on statins and proprotein convertase subtilisin/kexin Type 9 inhibitors for perioperative clinicians

Journal of Anaesthesiology Clinical Pharmacology, 2016
Statins are a mainstay of hyperlipidemia treatment. These drugs inhibit the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase and have beneficial effects on atherosclerosis including plaque stabilization, reduction of platelet activation, and ...
Terrence L Trentman, Steven G Avey, Harish Ramakrishna   +2 more
doaj   +1 more source

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source

Liver disease severity score predicts early and late mortality after lung transplantation: A United Network for Organ Sharing database analysisCentral MessagePerspective

JTCVS Open
Objective: Hepatorenal dysfunction after lung transplantation is associated with significant morbidity and mortality. The Model for End-stage Liver Disease excluding international normalized ratio (MELD-XI) score may predict outcomes after lung ...
Stephanie K. Tom, MD, Rachel A. Holstein, MPH, Clayton J. Rust, MD, Sandra Carpenter, MD, Humza Naqvi, MHS, Christopher L. He, BS, Ailin Tang, BS, Supreet S. Randhawa, MS, Amshumanth M. Chakragiri, BS, Maria V. Aslam, PhD, MPH, Michael E. Halkos, MD, MSc, Jeffrey Javidfar, MD, Lorenzo Zaffiri, MD, PhD, Muath M. Bishawi, MD, PhD, Mani A. Daneshmand, MD, Joshua L. Chan, MD   +15 more
doaj   +1 more source

Operations carried out and perioperative outcomes.

, 2015
Operations carried out and perioperative outcomes.
Janelle Rekman (712879), Kristopher P. Croome (712880), Fady K. Balaa (712882), Guillaume Martel (169332), Jeff Hawel (712878), Roberto Hernandez-Alejandro (712883), Kimberly Bertens (712881)   +6 more
core   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

BMI and its association with patient-reported outcome measures following revision hip surgery

Bone & Joint Open
Aims: Obesity is associated with increased surgical complexity and poorer postoperative outcomes after primary total hip arthroplasty (THA), yet its impact on revision THA remains unclear.
Rachel Baumber, Ahmed Mehmood, Robert McCulloch, Snehal M. Pinto Pereira, Eleanor Warwick, Alister Hart, S. Ramani Moonesinghe, PQIP delivery team, PQIP collaborative, On behalf of the PQIP delivery team and collaborative   +9 more
doaj   +1 more source

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

Advanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang, Jiachen Wang, Taozhi Wang, Yanling Li, Youyi Zhao, Guanghui Hao, Peiqin Gong, Ruling Chen, Yilin Fang, Shengxi Wu, Haopeng Zhang, Hui Zhang   +11 more
wiley   +1 more source

Mayo adhesive probability score predicts perioperative outcomes of laparoscopic adrenalectomy: a systematic review and meta-analysis

Frontiers in Oncology
ObjectiveThis meta-analysis aims to systematically evaluate the association between the Mayo Adhesive Probability (MAP) score and perioperative outcomes of laparoscopic adrenalectomy (LA) for benign adrenal tumors, and to explore the value of the MAP ...
Zhiqiang Zeng, Yang He, Yang He, Peng Ji, Peng Ji, Lunhong Zou, Tao Li, Yubo Zhou, Yubo Zhou, Tao Zhou, Huan Zhao, Xionglin Hu, Wangbing Chen, Wubin Chen   +13 more
doaj   +1 more source

A Neutrophil Membrane‐Encapsulated Pd/hCeO2 Nanoformulation for Alleviating Age‐Dependent Perioperative Neurocognitive Disorders

Advanced Science, EarlyView.
This study reports a neutrophil membrane‐encapsulated Pd/hCeO2 nanozyme (PCN) for targeted treatment of perioperative neurocognitive disorders (PND) in aged mice. PCN inhibits glycolysis‐driven microglial activation and neuroinflammation, improves mitochondrial respiration, and maintains blood‐brain barrier integrity and synaptic function, ultimately ...
Lili Huang, Jiahui Cheng, Huan Xu, Qiang Zhang, Xiao Zhang, Ye Liu, Yizhe Zhang, Wanbing Dai, Zhi Xiong, Linghuan Guo, Lingling Xu, Wen Wang, Xin Xu, Yan Zhou, Weifeng Yu, Bo Li, Diansan Su, Daxiang Wen   +17 more
wiley   +1 more source

Impact of Tumor Characteristics and Waiting Time on Perioperative Outcomes and Mortality in HCC Patients Underwent Living Donor Liver Transplantation تأثير خصائص الورم ووقت الانتظار على نتائج ما حول الجراحة ومعدل الوفيات لدى مرضى سرطان الخلايا الكبدي

Ain Shams Medical Journal
Background: The impact of tumor-related and patient-related parameters on perioperative surgical outcomes following living donor liver transplantation (LDLT) remains insufficiently explored.Aim: To evaluate the relationship between preoperative ...
Rasha Refaie, Moamen Ismail, Ahmed Abd-Elsalam, Mohsen Aly, Mahmoud Elmeteini   +4 more
doaj   +1 more source