Background Cancer surgery is necessary and life-saving. However, the majority of patients develop postoperative recurrence and metastasis, which are the main causes of cancer-related deaths.
Orneala Bakos +3 more
doaj +1 more source
The challenge of perioperative pain management in opioid-tolerant patients [PDF]
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F +9 more
core +2 more sources
Tourniquetless Total Knee Arthroplasty With Modern Perioperative Protocols Decreases Pain and Opioid Consumption in Women [PDF]
Background This study examined whether a modern total knee arthroplasty (TKA) protocol without a tourniquet results in less patient-reported pain and in-hospital opioid consumption compared to TKA with a tourniquet.
Dilley, Julian E. +4 more
core +1 more source
Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression [PDF]
Background: Endocannabinoids (ECs) are rapidly acting immune-modulatory lipid-signaling molecules that are important for adaptation to stressful and aversive situations. They are known to interact with glucocorticoids and other stress-responsive systems.
Beiras-Fernandez, Andres +9 more
core +1 more source
Glycaemic control in the perioperative period [PDF]
The prevalence of type 2 diabetes mellitus and the potential for perioperative dysglycaemia (hyperglycaemia, hypoglycaemia, stress-induced hyperglycaemia, or glucose variability) continue to increase dramatically. The majority of investigations on perioperative glycaemic control focused on critically ill patients and concentrated on goals of therapy ...
J J, Sebranek +2 more
openaire +2 more sources
Key points in reducing transfusion requirements in perioperative period [PDF]
Surgical intervention can lead to blood loss either through perioperative complications, or through disease severity until surgery. For this reason, mastering the main strategies to improve surgical patients’ haematological status, to reduce transfusion ...
Mirela Tiglis +4 more
doaj +1 more source
Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G +6 more
core +2 more sources
Statin Therapy within the Perioperative Period [PDF]
STATINS are highly effective in lowering serum cholesterol concentrations through 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase inhibition and thus are central to the primary and secondary prevention of cardiovascular disease. More than 50% of patients undergoing major vascular surgery and 80% undergoing cardiac surgery are on chronic ...
Yannick Le Manach +4 more
openaire +2 more sources
Risk Factors of Intraoperative Dysglycemia in Elderly Surgical Patients [PDF]
BACKGROUNDː Dysglycemia is associated with adverse outcome including increased morbidity and mortality in surgical patients. Acute insulin resistance due to the surgical stress response is seen as a major cause of so-called stress hyperglycemia. However,
Knaak, Cornelia +8 more
core +1 more source
INFUSION THERAPY IN PERI-OPERATIVE PERIOD
Goal: to familiarize Russian anesthesiologists with the most recent data of the evidence-based medicine about peri-operative infusion therapy. The right choice of the infusion therapy strategy and tactics is a mandatory component of the successful ...
V. V. Likhvantsev
doaj +1 more source

