Results 41 to 50 of about 250,732 (360)

Acquired hemophilia A developing in the perioperative period of pancreatoduodenectomy: a report of two cases

Surgical Case Reports, 2023
Background Acquired hemophilia A (AHA) is a rare disease characterized by a prolonged activated partial thromboplastin time (aPTT) and the production of coagulation factor VIII inhibitors.
Hidemasa Kubo, Ryo Ashida, Katsuhisa Ohgi, Masafumi Fukaya, Naoki Umezaki, Mihoko Yamada, Shimpei Otsuka, Katsuhiko Uesaka, Teiichi Sugiura   +8 more
doaj   +1 more source

The moderating role of adverse childhood experiences in the relationship between workplace incivility and suboptimal health status among nurses

BMC Psychology
Background Nurses, as the largest and most patient-facing group in healthcare systems, play a vital role in delivering high-quality care. However, they constantly work in high-risk and high-stress environments.
Xue Zhang, Xiaona Zhang
doaj   +1 more source

Influence of different regimens of volumetric therapy on perioperative intestinal flora in the surgical patients with pancreas tumor, a randomized controlled trial study

BMC Anesthesiology, 2022
Background It is not clear whether the perioperative intestinal microenvironment of patients undergoing pancreatic tumor surgery is affected by intraoperative fluid therapy.
Xiaojian Lu, Ying Wang, Yan Luo, Buwei Yu   +3 more
doaj   +1 more source

Is Normothermia Maintained in the Operating Room?

Dubai Medical Journal, 2021
Background: Inadvertent hypothermia is one of the most common problems in the perioperative period. Providing and maintaining normothermia is very important in preventing inadvertent perioperative hypothermia as well as complications. Purpose: The aim of
Ikbal Cavdar, Didem Kandemir, Ezgi Seyhan Ak, Nuray Akyuz   +3 more
doaj   +1 more source

Designing the ideal perioperative pain management plan starts with multimodal analgesia. [PDF]

, 2018
Multimodal analgesia is defined as the use of more than one pharmacological class of analgesic medication targeting different receptors along the pain pathway with the goal of improving analgesia while reducing individual class-related side effects ...
Mariano, Edward R., Schwenk, Eric S.
core   +1 more source

Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]

, 2019
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G, Diaconu, Camelia C, Gaman, Mihnea A, Manea, Maria, Marcu, Dragos R, Pantea Stoian, Anca, Stanescu, Ana M   +6 more
core   +2 more sources

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

STATINS USE IN THE PERIOPERATIVE PERIOD ACCORDING TO THE EVIDENCE-BASED MEDICINE

Рациональная фармакотерапия в кардиологии, 2015
Optimization of pharmacotherapy in the preoperative period is the cornerstone of the risk modification of cardiovascular complications in the perioperative period. Particular attention has recently been focused on statins use. Evidence base of this drugs
V. V. Samoylenko, O. P. Shevchenko, V. I. Burtsev   +2 more
doaj   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source