Results 1 to 10 of about 375,318 (175)

The PINK1 Activator Niclosamide Mitigates Mitochondrial Dysfunction and Thermal Hypersensitivity in a Paclitaxel-Induced Drosophila Model of Peripheral Neuropathy

Biomedicines, 2022
Paclitaxel is a widely used anticancer drug that induces dose-limiting peripheral neuropathy. Mitochondrial dysfunction has been implicated in paclitaxel-induced neuronal damage and in the onset of peripheral neuropathy. We have previously shown that the
Hye-Ji Jang, Young-Yeon Kim, Kang-Min Lee, Jung-Eun Shin, Jeanho Yun   +4 more
doaj   +1 more source

Peripheral mechanisms of peripheral neuropathic pain

Frontiers in Molecular Neuroscience, 2023
Peripheral neuropathic pain (PNP), neuropathic pain that arises from a damage or disease affecting the peripheral nervous system, is associated with an extremely large disease burden, and there is an increasing and urgent need for new therapies for treating this disorder.
Paola Pacifico, James S. Coy-Dibley, Richard J. Miller, Daniela M. Menichella   +3 more
openaire   +3 more sources

The “Direct tip injection in occlusive lesions (DIOL)” fashion

CVIR Endovascular, 2021
Background The successful intervention for peripheral artery disease is limited by complex chronic total occlusions (CTOs). During CTO wiring, without the use of intravascular or extravascular ultrasound, the guidewire position is unclear, except for ...
Takuya Haraguchi, Tsutomu Fujita, Yoshifumi Kashima, Masanaga Tsujimoto, Tomohiko Watanabe, Takuro Sugie, Daisuke Hachinohe, Umihiko Kaneko, Ken Kobayashi, Daitaro Kanno, Katsuhiko Sato   +10 more
doaj   +1 more source

The “needle re-entry” technique for infrainguinal arterial calcified occlusive lesions

CVIR Endovascular, 2021
Background Vascular calcification is a predictor of poor clinical outcome during and after endovascular intervention. Guidewire crossing techniques and devices have been developed, but chronic total occlusions (CTOs) with severe calcification often ...
Takuya Haraguchi, Yoshifumi Kashima, Masanaga Tsujimoto, Tomohiko Watanabe, Hidemasa Shitan, Takuro Sugie, Daisuke Hachinohe, Umihiko Kaneko, Ken Kobayashi, Daitaro Kanno, Katsuhiko Sato, Tsutomu Fujita   +11 more
doaj   +1 more source

The “Fracking” technique: a novel approach to crack deep calcified plaque in the common femoral artery with hydraulic pressure

CVIR Endovascular, 2021
Background The patency achieved by conventional peripheral interventions for atherosclerotic lesions in the common femoral artery (CFA), called the “no stenting zone”, is not superior to that achieved by surgical endarterectomy due to calcified plaque ...
Takuya Haraguchi, Tsutomu Fujita, Yoshifumi Kashima, Masanaga Tsujimoto, Tsuyoshi Takeuchi, Yutaka Tadano, Daisuke Hachinohe, Umihiko Kaneko, Ken Kobayashi, Daitaro Kanno, Katsuhiko Sato   +10 more
doaj   +1 more source

Development and validation of a prediction model to estimate risk of acute pulmonary embolism in deep vein thrombosis patients

Scientific Reports, 2022
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis (DVT) or pulmonary embolism (PE). Not all DVT patients carry the same risk of developing acute pulmonary embolism (APE).
You Li, Yuncong He, Yan Meng, Bowen Fu, Shuanglong Xue, Mengyang Kang, Zhenzhen Duan, Yan Chen, Yifan Wang, Hongyan Tian   +9 more
doaj   +1 more source

Deep vein thrombosis due to May-Thurner syndrome: a case report

BMC Cardiovascular Disorders, 2020
Background May-Thurner syndrome (MTS) or Cockett’s syndrome is a rare clinical syndrome, which refers to the compression of the left common iliac vein (LCIV) by right common iliac artery and vertebral body. Complications of MTS include deep vein thrombus
Yan Meng, Hao Qin, Qiang Ma, Junbo Zhang, Bo Zhang, Honggang Pang, Qian Yin, Hongyan Tian   +7 more
doaj   +1 more source

The effect of local warming before vascular access on vascular access indicators in adult patients receiving chemotherapy: A systematic review

Nursing and Midwifery Studies, 2021
Background: Intravenous (IV) cannulation is difficult, especially in patients undergoing chemotherapy due to frequent exposure to venous catheterization as well as the destructive effects of chemotherapy drugs on the vessel wall.
Abbas Heydari, Zahra-Sadat Manzari, Hasan Khalili   +2 more
doaj   +1 more source

A review of neonatal peripherally inserted central venous catheters in extremely or very low birthweight infants based on a 3-year clinical practice: Complication incidences and risk factors

Frontiers in Pediatrics, 2022
BackgroundThe application of peripherally inserted central venous catheters (PICCs) in neonates has proven effective in avoiding repetitive insertions and excessive use of transfusion consumables.
Yaohua Wu, Yaohua Wu, Jing Yan, Jing Yan, Mengyan Tang, Mengyan Tang, Yanling Hu, Yanling Hu, Xingli Wan, Xingli Wan, Xiaowen Li, Xiaowen Li, Qiong Chen, Qiong Chen, Xia Li, Xia Li   +15 more
doaj   +1 more source

Diagnostic Value of Serum Biomarkers for Differentiating Central and Peripheral Causes of Acute Vertigo

Frontiers in Medicine, 2020
Background: In patients presenting with acute vertigo or dizziness, distinguishing central from peripheral is a diagnostic challenge. This study investigated potential serum markers for differentiating central and peripheral vertigo in patients with ...
Jong-Hee Sohn, Chul-Ho Kim, Sang-Hwa Lee, Jong Ho Kim, Jae Jun Lee   +4 more
doaj   +1 more source