Results 111 to 120 of about 3,012,145 (371)

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Painful diabetic peripheral neuropathy among Saudi diabetic patients is common but under-recognized: Multicenter cross-sectional study at primary health care setting

Journal of Family and Community Medicine, 2018
OBJECTIVE: The aim of this study was to assess the prevalence of painful diabetic peripheral neuropathy (PDPN) and its associated risk factors in patients with type 2 diabetes mellitus attending primary health care (PHC) in Saudi Arabia.
Metab A Algeffari
doaj   +1 more source

Peripheral urbanization: Autoconstruction, transversal logics, and politics in cities of the global south

, 2017
Many cities around the world have been largely constructed by their residents, who build not only their own houses, but also frequently their neighborhoods.
Teresa P. R. Caldeira
semanticscholar   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients

Annals of Indian Academy of Neurology, 2011
Background: Rheumatoid arthritis is a multi-system autoimmune disorder predominantly involving multiple small and large joints along with certain extra-articular manifestations.
Monodeep Biswas, Arghya Chatterjee, Sudip Kumar Ghosh, S Dasgupta, Kartik Ghosh, P K Ganguly   +5 more
doaj   +1 more source

Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy

Frontiers in Molecular Neuroscience, 2017
Chemotherapy-induced neuropathy is a common, dose-dependent adverse effect of several antineoplastics. It can lead to detrimental dose reductions and discontinuation of treatment, and severely affects the quality of life of cancer survivors.
Hana Starobova, I. Vetter
semanticscholar   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1910-1917, December 2022., 2022
Abstract Objective Flail arm syndrome (FAS) is one of the atypical subtypes of amyotrophic lateral sclerosis (ALS). Mutations in hnRNPA1 encoding heterogeneous nuclear ribonucleoprotein (hnRNP) A1 are a rare genetic cause of ALS. Herein, marked clinical heterogeneity of FAS in a pedigree with a known hnRNPA1 variant was described to raise early ...
Xiaochen Han, Feixia Zhan, Yuxin Yao, Li Cao, Jianguo Liu, Sheng Yao   +5 more
wiley   +1 more source

The Function of MicroRNAs in B-Cell Development, Lymphoma, and Their Potential in Clinical Practice

Frontiers in Immunology, 2018
B-cell formation, development, and differentiation are complex processes regulated by several mechanisms. Recently, there has been growing evidence indicating that microRNAs (miRNAs) are important for normal B-cell lineage development.
Bing Zheng, Bing Zheng, Zhijiang Xi, Zhijiang Xi, Rong Liu, Rong Liu, Wei Yin, Zhiwei Sui, Boxu Ren, Boxu Ren, Heather Miller, Quan Gong, Quan Gong, Chaohong Liu   +13 more
doaj   +1 more source

Peripheral convex expansions of resonance graphs [PDF]

arXiv, 2019
In this paper, we show that the resonance graph of a plane elementary bipartite graph $G$ can be obtained from an edge by a sequence of peripheral convex expansions with respect to a reducible face decomposition of $G$ if and only if the infinite face of $G$ is forcing.
arxiv