Results 111 to 120 of about 3,916,297 (351)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

CircST6GAL1 knockdown alleviates pulmonary arterial hypertension by regulating miR‐509‐5p/multiple C2 and transmembrane domain containing 2 axis

The Clinical Respiratory Journal
Background Hypertension is a main contributing factor of cardiovascular diseases; deregulated circular RNAs are involved in the pathogenesis of pulmonary arterial hypertension (PAH).
Xing Zhang, Hao Qin, Qiang Ma, Junbo Zhang, Hongyan Tian, Yan Meng   +5 more
doaj   +1 more source

Composition of myelin from peripheral and central nervous systems of the squirrel monkey

Journal of Lipid Research, 1967
Myelin was prepared from the brachial plexus and cervical spinal cord of adult squirrel monkeys (Saimiri sciureus). Brachial plexus myelin contained a larger amount of sphingomyelin and smaller amounts of cholesterol, lipid galactose, ethanolamine ...
L.A. Horrocks
doaj   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Islet-expressed circular RNAs are associated with type 2 diabetes status in human primary islets and in peripheral blood [PDF]

, 2020
Shahnaz Haque, Ryan M. Ames, Karen Moore, Benjamin P. Lee, Nicola Jeffery, Lorna W. Harries   +5 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

PREVALENCE OF PHLEBITIS RELATED TO THE USE OF PERIPHERAL INTRAVENOUS DEVICES IN CHILDREN

Cogitare Enfermagem, 2018
Objective: To assess the prevalence of phlebitis, related to the use of peripheral intravenous devices in children in a teaching hospital. Method: A quantitative, descriptive and retrospective study, based in data taken from the phlebitis ...
Elessandra Souza Bitencourt, Camila Nunes Leal, Radamés Boostel, Verônica de Azevedo Mazza, Jorge Vinícius Cestari Felix, Edivane Pedrolo   +5 more
doaj   +1 more source

Mitochondrial DNA Copy Number in Peripheral Blood Is Independently Associated with Visceral Fat Accumulation in Healthy Young Adults [PDF]

, 2014
Jee‐Yon Lee, Duk‐Chul Lee, Jee‐Aee Im, Ji‐Won Lee   +3 more
openalex   +1 more source

Machinability of Different Wood-Plastic Composites during Peripheral Milling [PDF]

, 2022
Zhaolong Zhu, Dietrich Buck, Jinxin Wang, Zhanwen Wu, Wei Xu, Xiaolei Guo   +5 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source