Results 11 to 20 of about 3,061,254 (347)
Peripheral mechanisms of peripheral neuropathic pain
Frontiers in Molecular Neuroscience, 2023 Peripheral neuropathic pain (PNP), neuropathic pain that arises from a damage or disease affecting the peripheral nervous system, is associated with an extremely large disease burden, and there is an increasing and urgent need for new therapies for treating this disorder.
Paola Pacifico +3 more
openaire +3 more sources
Epidemiology of Peripheral Artery Disease and Polyvascular Disease
Circulation Research, 2021 Atherosclerotic lower extremity peripheral artery disease (PAD) is increasingly recognized as an important cause of cardiovascular morbidity and mortality that affects >230 million people worldwide.
A. Aday, K. Matsushita
semanticscholar +1 more source
Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus
Nature Reviews Neurology, 2021 Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates pathological alterations in central and peripheral immune responses that change over time.
Brianne M. Bettcher +3 more
semanticscholar +1 more source
Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia
Journal of Infectious Diseases, 2020 Background In December 2019, novel coronavirus (SARS-CoV-2) pneumonia (COVID-19) was reported in Wuhan and has since rapidly spread throughout China.
Fan Wang +9 more
semanticscholar +1 more source
Rivaroxaban in Peripheral Artery Disease after Revascularization.
New England Journal of Medicine, 2020 BACKGROUND Patients with peripheral artery disease who have undergone lower-extremity revascularization are at high risk for major adverse limb and cardiovascular events. The efficacy and safety of rivaroxaban in this context are uncertain.
Marc P. Bonaca +21 more
semanticscholar +1 more source
Journal of Experimental Medicine, 2003 CD4+CD25+ regulatory T cells (Treg) are instrumental in the maintenance of immunological tolerance. One critical question is whether Treg can only be generated in the thymus or can differentiate from peripheral CD4+CD25− naive T cells.
Wanjun Chen +7 more
semanticscholar +1 more source
Peripheral inflammation and blood–brain barrier disruption: effects and mechanisms
CNS Neuroscience & Therapeutics, 2020 The blood–brain barrier (BBB) is an important physiological barrier that separates the central nervous system (CNS) from the peripheral circulation, which contains inflammatory mediators and immune cells. The BBB regulates cellular and molecular exchange
Xiaowen Huang +2 more
semanticscholar +1 more source
Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation
Nature, 2013 Intestinal microbes provide multicellular hosts with nutrients and confer resistance to infection. The delicate balance between pro- and anti-inflammatory mechanisms, essential for gut immune homeostasis, is affected by the composition of the commensal ...
Nicholas Arpaia +10 more
semanticscholar +1 more source
Frontiers in Medicine, 2020 Background: In patients presenting with acute vertigo or dizziness, distinguishing central from peripheral is a diagnostic challenge. This study investigated potential serum markers for differentiating central and peripheral vertigo in patients with ...
Jong-Hee Sohn +4 more
doaj +1 more source
Effects of Central and Peripheral Fatigue on Impact Characteristics during Running
Sensors, 2022 Fatigue and impact can represent an injury risk factor during running. The objective of this study was to compare the impact transmission along the locomotor system between the central and peripheral fatigued states during running.
Alberto Encarnación-Martínez +3 more
doaj +1 more source