Results 51 to 60 of about 883,236 (393)

Ankle brachial index for the diagnosis of lower limb peripheral arterial disease.

Cochrane Database of Systematic Reviews, 2016
BACKGROUND Peripheral arterial disease (PAD) of the lower limb is common, with prevalence of both symptomatic and asymptomatic disease estimated at 13% in the over 50 age group.
F. Crawford, K. Welch, A. Andras, F. Chappell   +3 more
semanticscholar   +1 more source

Statins in Peripheral Arterial Disease [PDF]

Current Pharmaceutical Design, 2018
Peripheral arterial disease (PAD) is a common atherosclertico condition affecting the lower extremities. PAD patients share similar cardiovascular risk factors to coronary artery disease patients and suffer from increased cardiovascular morbidity and mortality.
Chiesa, ST, Papageorgiou, N, Charakida, M   +2 more
openaire   +3 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Sex disparities in peripheral arterial occlusive disease

Angiologia e Cirurgia Vascular, 2023
INTRODUCTION: Recently published studies on peripheral arterial occlusive disease (PAOD) have revealed marked sex disparities in patient selection and treatment outcomes.
Leonor Baldaia, Luís F. Antunes, Cândida G. Silva, Miguel Silva, Eduardo Silva, Celso Nunes, Vânia Constâncio, Manuel Fonseca   +7 more
doaj   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Plasma osteoprotegerin is related to carotid and peripheral arterial disease, but not to myocardial ischemia in type 2 diabetes mellitus

Cardiovascular Diabetology, 2011
Background Cardiovascular disease (CVD) is frequent in type 2 diabetes mellitus patients due to accelerated atherosclerosis. Plasma osteoprotegerin (OPG) has evolved as a biomarker for CVD.
Høilund-Carlsen Poul F, Johansen Allan, Poulsen Tina S, Hosbond Susanne, Dahl Jordi, Nybo Mads, Poulsen Mikael K, Beck-Nielsen Henning, Rasmussen Lars M, Henriksen Jan E   +9 more
doaj   +1 more source

Diabetic foot disease and oedema [PDF]

, 2013
Diabetic foot ulcers (DFUs) are common and disabling, giving rise to significant morbidity and mortality as well as worldwide socioeconomic problems. Despite treatment, DFUs readily become chronic wounds and may lead to major lower limb amputations.
Ho, TK, Leigh, RD, Tsui, J
core   +1 more source

Twenty‐Year Predictors of Peripheral Arterial Disease Compared With Coronary Heart Disease in the Scottish Heart Health Extended Cohort (SHHEC)

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Coronary heart disease and peripheral arterial disease (PAD) affect different vascular territories. Supplementing baseline findings with assays from stored serum, we compared their 20‐year predictors.
H. Tunstall-Pedoe, S. Peters, M. Woodward, A. Struthers, J. Belch   +4 more
semanticscholar   +1 more source

Peripheral Artery Disease and Stroke

Journal of Cardiovascular Echography, 2018
Peripheral artery disease (PAD) and stroke can occur as vascular complication of anticancer treatment. Although the mechanisms, monitoring, and management of cardiotoxicities have received broad attention, vascular toxicities remain often underrecognized.
Zito, Concetta, Manganaro, Roberta, Carerj, Scipione, Antonini-Canterin, Francesco, Benedetto, Frank   +4 more
openaire   +4 more sources

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source