Results 51 to 60 of about 883,236 (393)
Ankle brachial index for the diagnosis of lower limb peripheral arterial disease.
BACKGROUND Peripheral arterial disease (PAD) of the lower limb is common, with prevalence of both symptomatic and asymptomatic disease estimated at 13% in the over 50 age group.
F. Crawford+3 more
semanticscholar +1 more source
Statins in Peripheral Arterial Disease [PDF]
Peripheral arterial disease (PAD) is a common atherosclertico condition affecting the lower extremities. PAD patients share similar cardiovascular risk factors to coronary artery disease patients and suffer from increased cardiovascular morbidity and mortality.
Chiesa, ST+2 more
openaire +3 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Sex disparities in peripheral arterial occlusive disease
INTRODUCTION: Recently published studies on peripheral arterial occlusive disease (PAOD) have revealed marked sex disparities in patient selection and treatment outcomes.
Leonor Baldaia+7 more
doaj +1 more source
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski+13 more
wiley +1 more source
Background Cardiovascular disease (CVD) is frequent in type 2 diabetes mellitus patients due to accelerated atherosclerosis. Plasma osteoprotegerin (OPG) has evolved as a biomarker for CVD.
Høilund-Carlsen Poul F+9 more
doaj +1 more source
Diabetic foot disease and oedema [PDF]
Diabetic foot ulcers (DFUs) are common and disabling, giving rise to significant morbidity and mortality as well as worldwide socioeconomic problems. Despite treatment, DFUs readily become chronic wounds and may lead to major lower limb amputations.
Ho, TK, Leigh, RD, Tsui, J
core +1 more source
Background Coronary heart disease and peripheral arterial disease (PAD) affect different vascular territories. Supplementing baseline findings with assays from stored serum, we compared their 20‐year predictors.
H. Tunstall-Pedoe+4 more
semanticscholar +1 more source
Peripheral Artery Disease and Stroke
Peripheral artery disease (PAD) and stroke can occur as vascular complication of anticancer treatment. Although the mechanisms, monitoring, and management of cardiotoxicities have received broad attention, vascular toxicities remain often underrecognized.
Zito, Concetta+4 more
openaire +4 more sources
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang+5 more
wiley +1 more source