Results 91 to 100 of about 3,965,736 (309)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

, 2014
Peripheral T-cell lymphoma (PTCL) encompasses a heterogeneous group of neoplasms with generally poor clinical outcome. Currently 50% of PTCL cases are not classifiable: PTCL-not otherwise specified (NOS).
Connors, J.M., Wilcox, R.A., Staudt, L.M., Rimsza, L.M., Rosenwald, A., Smith, L., the International Peripheral T-cell Lymphoma, Project, Gascoyne, R.D., Iqbal, J., Braziel, R.M., Lim, S.T., Au, W.Y., Wang, C., Geissinger, E., Gaulard, P., Tan, S.Y., Nakamura, S., Vose, J., Seto, M., Weisenburger, D.D., Delabie, J., Lymphoma Leukemia Molecular Profiling, Project, Jaffe, E.S., Cook, J.R., Guo, S., Armitage, J., Martinez, A., Berger, F., Chan, W.C., Greiner, T.C., Tubbs, R.R., Campo, E., Pileri, S.A., Wright, G., Teh, B.T., Ott, G., Piccaluga, P.P., de Leval, L.   +37 more
core   +1 more source

A study of ovarian cancer patients treated with dose-intensive chemotherapy supported with peripheral blood progenitor cells mobilised by filgrastim and cyclophosphamide [PDF]

, 1996
Summary We have shown that large numbers of haemopoietic progenitor cells are mobilised into the blood after filgrastim [granulocyte colony-stimulating factor (G-CSF)] alone and filgrastim following cyclophosphamide chemotherapy in previously untreated
Dexter, TM, C Gill, D Crowther, Gill, C, NG Testa, Weaver, A, Testa, NG, A Weaver, B Jenkins, R Pettengell, Collins, CD, Crowther, D, A Watson, Pettengell, R, Wrigley, E, J Chang, TM Dexter, Watson, A, CD Collins, E Wrigley, Chang, J, Jenkins, B   +21 more
core   +1 more source

Immunomodulatory Effect of Pregnancy on Leukocyte Populations in Patients With Multiple Sclerosis: A Comparison of Peripheral Blood and Decidual Placental Tissue

Frontiers in Immunology, 2019
Pregnancy is a naturally occurring disease modifier of multiple sclerosis (MS) associated with a substantial reduction in relapse rate. To date, attempts to explain this phenomenon have focused on systemic maternal immune cell composition, with ...
Michela Spadaro, Michela Spadaro, Serena Martire, Serena Martire, Luca Marozio, Daniela Mastromauro, Elena Montanari, Simona Perga, Simona Perga, Simona Perga, Francesca Montarolo, Francesca Montarolo, Francesca Montarolo, Federica Brescia, Federica Brescia, Alessia Balbo, Alessia Balbo, Giovanni Botta, Chiara Benedetto, Antonio Bertolotto, Antonio Bertolotto   +20 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Laboratory analyses for evaluation of platelet disorders and platelet concentrates [PDF]

, 2006
High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Peripheral-blood B-lymphocyte subsets at baseline of the 9 patients diagnosed with Whipple’s disease (WD).

, 2019
Peripheral-blood B-lymphocyte subsets at baseline of the 9 patients diagnosed with Whipple’s disease (WD).
Marion Herbette (5533373), Alain Saraux (356420), Valérie Devauchelle-Pensec (3134643), Christophe Jamin (356424), Divi Cornec (795436), Dewi Guellec (6406937), Jacques Olivier Pers (795435), Maëlle Le Goff (6406934), Thierry Marhadour (3134649), Clara Le Guillou (6406943), Sandrine Jousse-Joulin (795429), Jean Michel Cauvin (6406940), Yves Renaudineau (6020402)   +12 more
core   +1 more source

Peripheral blood TCR repertoire improves early detection across multiple cancer types utilizing a cancer predictor

Frontiers in Oncology
IntroductionIn the early asymptomatic stages of cancer, the immune system initiates a targeted response against tumor-associated antigens. During this phase, the immune system specifically identifies tumor antigens and triggers the clonal expansion of ...
Yinglei Tang, Xinyi Liao, Bo Liao, Bo Liao, Dejun Peng, Dejun Peng, Qingbo Li, Qingbo Li   +7 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source