Results 231 to 240 of about 3,965,736 (309)

Peripheral blood transcriptomic signature is associated with cognitive impairment and freezing of gait in Parkinson's disease: a data-driven approach. [PDF]

NPJ Parkinsons Dis
Lee R, Park M.
europepmc   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

RNA modifications in peripheral blood are associated with acute coronary syndrome. [PDF]

J Mol Cell Cardiol Plus
Sopic M, Stopa V, Munjas J, Davidović A, Vukmirović L, Cvijanović D, Milanov M, Martelli F, Bernardin F, Legrave NM, Devaux Y.   +10 more
europepmc   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Peripheral Blood Transcriptomic Features Distinguishing Postpartum Depression from Major Depressive Disorder and Healthy Postpartum Controls. [PDF]

Int J Womens Health
Lin L, Tang H, Kuang H, Yang Y, Zhao H.
europepmc   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Peripheral blood DNA methylation partially reports on immune cell type composition in the frontal brain. [PDF]

Brain Behav Immun Health
Meijer M, Fu MPY, Navarro-Delgado EI, Engelbrecht HR, Turecki G, Chan MH, Kobor MS.   +6 more
europepmc   +1 more source

Human‐Scale Rotating Magnetic Field Delivery With Permanent Magnets Under Anatomic and Robotic Constraints

Advanced Robotics Research, EarlyView.
Rotating magnetic fields (RMFs) are widely used for microrobot propulsion and control. We show that RMF generation with permanent magnets is mechanically feasible for many limb and intracranial applications but becomes constrained for thoracic targets.
Tuan‐Anh Le, Husnu Halid Alabay, Anika Sivarasa, Gia‐Minh Hoang, Hakan Ceylan   +4 more
wiley   +1 more source

Peripheral Blood Biomarkers for Predicting the Efficacy of Neoadjuvant Immunochemotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma. [PDF]

J Inflamm Res
Shen Y, Wang J, Wang R, Liu Z, Pan Y, Du Y, Dong M.   +6 more
europepmc   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source