Results 11 to 20 of about 298,696 (311)

USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study [PDF]

Therapeutics and Clinical Risk Management, 2015
Sona Frankova,1 Milan Jirsa,2 Dusan Merta,3 Magdalena Neroldova,2 Petr Urbanek,4 Renata Senkerikova,1 Julius Spicak,1 Jan Sperl1 1Department of Hepatogastroenterology, 2Laboratory of Experimental Hepatology, 3Department of Anesthesiology, Resuscitation ...
Frankova S, Jirsa M, Merta D, Neroldova M, Urbanek P, Senkerikova R, Spicak J, Sperl J   +7 more
doaj   +1 more source

Protocol to quantify glycan-mediated binding between viral particles and human peripheral blood mononuclear cells using nanoluciferase [PDF]

, 2023
Prior to receptor engagement, a specific, non-electrostatic glycan-glycan interaction between viral particles and host cells may lengthen the dwell time of the virus at the cellular surface, thereby facilitating subsequent virus entry. Here, we present a
Mak, J, Johnson Mak, Spillings, BL, Belinda L. Spillings   +3 more
core   +1 more source

Population Pharmacokinetic Model of Plasma and Cellular Mycophenolic Acid in Kidney Transplant Patients from the CIMTRE Study

Drugs in R&D, 2020
Background and Objective Mycophenolate mofetil is widely used in kidney transplant recipients. Mycophenolate mofetil is hydrolysed by blood esterases to mycophenolic acid (MPA), the active drug.
François Riglet, Julie Bertrand, Aurélie Barrail-Tran, Céline Verstuyft, Hugues Michelon, Henri Benech, Antoine Durrbach, Valérie Furlan, Caroline Barau   +8 more
doaj   +1 more source

Oxidative stress-induced DNA damage and repair in human peripheral blood mononuclear cells: protective role of hemoglobin. [PDF]

PLoS ONE, 2013
BACKGROUND:DNA repair is a cellular defence mechanism responding to DNA damage caused in large part by oxidative stress. There is a controversy with regard to the effect of red blood cells on DNA damage and cellular response.
Anat Gafter-Gvili, Boris Zingerman, Benaya Rozen-Zvi, Yaacov Ori, Hefziba Green, Ido Lubin, Tsipora Malachi, Uzi Gafter, Michal Herman-Edelstein   +8 more
doaj   +1 more source

Occult Hepatitis C Virus Infection: Is it time to get more attention!? [PDF]

Records of Pharmaceutical & Biomedical Sciences, 2022
Occult hepatitis C virus infection (OCI) is broadly described as the presence of HCV-RNA in hepatocytes and/or peripheral blood mononuclear cells (PBMCs) in individuals who are HCV-RNA negative in serum by traditional diagnostic techniques.
Kholoud Elkashef
doaj   +1 more source

Abnormal telomere shortening of peripheral blood mononuclear cells and granulocytes in patients with chronic idiopathic neutropenia

Haematologica, 2012
Background Chronic idiopathic neutropenia is characterized by immune-mediated suppression of neutrophil production. Because patients with immune-mediated bone marrow failure syndromes display age-inappropriate telomere shortening in leukocytes, we ...
Konstantia I. Pavlaki, Maria-Christina Kastrinaki, Michail Klontzas, Maria Velegraki, Irene Mavroudi, Helen A. Papadaki   +5 more
doaj   +1 more source

Activation of peroxisome proliferator-activated receptor alpha in human peripheral blood mononuclear cells reveals an individual gene expression profile response [PDF]

, 2007
Peripheral blood mononuclear cells (PBMCs) are relatively easily obtainable cells in humans. Gene expression profiles of PBMCs have been shown to reflect the pathological and physiological state of a person.
Afman, Lydia A., Bouwens, M., Müller, Michael, Müller Michael, Afman, Lydia, Afman, Lydia A, Afman, L.A., Michael Müller, Bouwens Mark, Müller, M.R., Mark Bouwens, Afman Lydia A, Bouwens, Mark, Lydia A Afman   +13 more
core   +1 more source

CD14+ cells from peripheral blood positively regulate hematopoietic stem and progenitor cell survival resulting in increased erythroid yield

Haematologica, 2015
Expansion of erythroblasts from human peripheral blood mononuclear cells is 4- to 15-fold more efficient than that of CD34+ cells purified from peripheral blood mononuclear cells.
Esther Heideveld, Francesca Masiello, Manuela Marra, Fatemehsadat Esteghamat, Nurcan Yağcı, Marieke von Lindern, Anna Rita F. Migliaccio, Emile van den Akker   +7 more
doaj   +1 more source

Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]

, 2004
Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Seliger, Christian, Huss, Ralf, Kinston, Sarah, Gottgens, Berthold, Heil, Matthias, Sabine Moosmann, Matthias Heil, Christian Seliger, Sabine Sagebiel, Berthold Gottgens, Tibor Ziegelhoeffer, Moosmann, Sabine, Ralf Huss, Sarah Kinston, Ziegelhoeffer, Tibor, Sagebiel, Sabine   +15 more
core   +1 more source

Aggregation of mononuclear and red blood cells through an α4β1-Lu/basal cell adhesion molecule interaction in sickle cell disease

Haematologica, 2010
Background Abnormal interactions between red blood cells, leukocytes and endothelial cells play a critical role in the occurrence of the painful vaso-occlusive crises associated with sickle cell disease.
Vicky Chaar, Julien Picot, Olivier Renaud, Pablo Bartolucci, Ruben Nzouakou, Dora Bachir, Frédéric Galactéros, Yves Colin, Caroline Le Van Kim, Wassim El Nemer   +9 more
doaj   +1 more source