Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
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On-Table Versus Deferred Extubation After Paediatric Cardiac Catheterisation Under General Anaesthesia: A Retrospective Cohort Study. [PDF]
Gürsoy Çirkinoğlu G +7 more
europepmc +1 more source
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae +2 more
wiley +1 more source
Analysis of portal vein thrombosis prevalence and risk factors in neonates following umbilical venous catheterization: a systematic review and meta-analysis. [PDF]
Novaes RM, de Alcântara RV, Hessel G.
europepmc +1 more source
This preclinical study evaluated a novel controlled‐expansion expanded polytetrafluoroethylene (ePTFE)‐covered transjugular intrahepatic portosystemic shunt (TIPS) stent in 11 swine, demonstrating 100% technical success, excellent deployability, and durable 6‐month angiographic patency without thrombosis, migration, fracture, or device‐related toxicity.
Yi Xiang +15 more
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Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Right Heart Catheterization in a Patient With Breast Cancer: A Case Report. [PDF]
Tajima S +4 more
europepmc +1 more source
Intelligent Continuum Micromachines in Complex Confined Spaces
The cover depicts a conceptual design for an intelligent continuum micromachine entering a target capsule used in fusion‐energy research through its slender gas‐fill tube. By combining route‐adaptive deformation, embedded sensing, and a functional end effector, the robot could inspect hidden defects, assess local conditions, and support localized ...
Huayang Sai +7 more
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Oxygen utilization during moderate-intensity resistance and aerobic exercise in arrhythmogenic cardiomyopathy: the central role of the periphery. [PDF]
Wernhart S +5 more
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Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini +3 more
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The application effect of mini midline catheters in intravenous therapy for neurology patients: real-world evidence from eastern China. [PDF]
Ding X, Mao R, Ma T, Li X, Chen Y.
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