Results 221 to 230 of about 715,764 (296)

Early Multicenter Outcomes of Dedicated Transcatheter Aortic Valve Replacement for Left Ventricular Assist Device‐Associated Pure Aortic Regurgitation

open access: yesArtificial Organs, EarlyView.
LVAD‐associated aortic regurgitation impairs circulatory support, with limited surgical and off‐label options. In a multicenter registry (n = 30), the AR‐dedicated JenaValve Trilogy TAVR eliminated AR, achieving 96.7% (29/30) technical success and 93.3% (28/30) device success (VARC‐3), with 3.3% (1/30) 30‐day mortality.
Hristian Hinkov   +13 more
wiley   +1 more source

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

open access: yesArtificial Organs, EarlyView.
In this series of 19 DCD donors using TA‐NRP, 89.5% of hearts were successfully transplanted with no PGD, no postoperative ECMO, and no 30‐day mortality, demonstrating the feasibility and safety of this approach. ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged ...
Maria Benedetto   +11 more
wiley   +1 more source

A hemodynamic and biomarker study of pulmonary hypertension associated with heart failure: DISCOVER PH-HF. [PDF]

open access: yesJ Cardiovasc Med (Hagerstown)
Manni R   +11 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Intra-aortic adrenaline titration during cardiac arrest. [PDF]

open access: yesScand J Trauma Resusc Emerg Med
Manning JE   +3 more
europepmc   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn   +10 more
wiley   +1 more source

Limited opportunity for nursing students to perform practical nursing skills during clinical placements: a Scandinavian cross-sectional study. [PDF]

open access: yesInt J Nurs Stud Adv
Jonsson K   +8 more
europepmc   +1 more source

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum

open access: yesClinical Genetics, EarlyView.
Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz   +23 more
wiley   +1 more source

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