Results 81 to 90 of about 4,603,420 (293)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

The Value of Peripheral Enhancement Pattern for Diagnosing Thyroid Cancer Using Contrast-Enhanced Ultrasound

open access: yesInternational Journal of Endocrinology, 2018
Background. Contrast-enhanced ultrasound (CEUS) scanning can detect differences between thyroid tumors and surrounding tissues. However, enhancement patterns within nodules are insufficient for the diagnosis of thyroid carcinomas.
Yan Zhang   +5 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Characterization of contrast-mediated collinear interactions in the human visual system

open access: yesScientific Reports
Collinear modulation represents a fundamental building block of our perceptual world, and its study has enhanced our understanding of contrast sensitivity, spatial integration, and neural plasticity in the visual system.
Luca Battaglini   +5 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

The role of contrast sensitivity charts and contrast letter charts in clinical practice [PDF]

open access: yes, 1995
Practitioners frequently make clinical decisions based on changes in visual acuity. However, acuity is recognised to be only one aspect of visual performance.
Wood, Joanne M., Woods, Russell L
core  

Peripheral and central factors limiting the development of contrast sensitivity in Macaque monkeys

open access: yesVision Research, 1998
The aim of this study was to evaluate the contribution of peripheral and central factors to the development of visual sensitivity. We used the approach of (Pelli, 1981, 1990) to evaluate the hypothesis that intrinsic noise is high in infants compared with adults, and therefore sets an important limit on contrast sensitivity in infants.
Kiorpes, Lynne, Movshon, J.Anthony
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Left peripheral arguments and discourse interface strategies in Yucatec Maya [PDF]

open access: yes, 2012
Skopeteas S, Verhoeven E. Left peripheral arguments and discourse interface strategies in Yucatec Maya. In: Neeleman A, Kucerova I, eds. Contrasts and positions in information structure.
Verhoeven, Elisabeth   +5 more
core   +1 more source

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