Results 121 to 130 of about 3,422,495 (345)

Peripheral Facial Nerve Axotomy in Mice Causes Sprouting of Motor Axons Into Perineuronal Central White Matter: Time Course and Molecular Characterization [PDF]

, 2010
Generation of new axonal sprouts plays an important role in neural repair In the current study, we examined the appearance, composition and effects of gene deletions on intrabrainstem sprouts following peripheral facial nerve axotomy Axotomy was followed
Werner, A, Galiano, Mathias, Ruff, Crystal, Mathias Galiano, Werner, A., Gonitel, R, Werner, Alexander, Anderson, P., Raivich, G., Patrick N. Anderson, Prakasham Rumajogee, Pararajasingam, A, Bohatschek, M, Behrens, A, Galiano, M., Cuthill, Dan, Bohatschek, M., Acosta-Saltos, A, Makwana, Milan, Dan Cuthill, Rumajogee, P., Anderson, Patrick N., Ulrike Mayer, Acosta-Saltos, Alejandro, Anderson, PN, Behrens, Axel, Raivich, Gennadij, Pararajasingham, A, Gonitel, R., Rumajogee, Prakasham, Ruff, C., Ruff, C, Rumajogee, P, Wallace, AS, Acosta-Saltos, A., Alejandro Acosta‐Saltos, Marion Bohatschek, Axel Behrens, Makwana, M, Wallace, Adam S., Bohatschek, Marion, Gennadij Raivich, Mayer, U, Mayer, Ulrike, Wallace, A., Alexander Werner, Adam S. Wallace, Pararajasingham, Abirami, Behrens, A., Abirami Pararajasingham, Makwana, M., Cuthill, D., Crystal Ruff, Cuthill, D, Galiano, M, Gonitel, Roman, Roman Gonitel, Mayer, U., Milan Makwana, Pararajasingham, A., Raivich, G   +60 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Peripheral nerve injury with substance loss: fabrication and in vivo evaluation of new bioactive devices

, 2023
reservedSevere peripheral nerve injuries (PNI) are a challenge in clinical practice as no commercial device guarantees outcomes better than those provided by autografts. In this context, there has been intense research devoted to improving nerve conduits
D'OSUALDO, ALICE
core  

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. [PDF]

, 2012
The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Jenkins, Billy, Turmaine, Mark, Mirsky, Rhona, Quintes, Susanne, Wicher, GK, Chabrol, Elodie, Latouche, Morwena, Chabrol, E, Behrens, A, Mirsky, R, Woodhoo, Ashwin, Jenkins, B, Mitter, Richard, Quintes, S, Turmaine, M, Greensmith, L, Woodhoo, A, Mitter, R, Behrens, Axel, Raivich, Gennadij, Wicher, Grzegorz K.,, Latouche, M, Banerjee, Annbily, Arthur-Farraj, PJ, Wilton, DK, Banerjee, A, Rahman, Mary, Jessen, KR, Rahman, M, Greensmith, Linda, Raivich, G, Arthur-Farraj, Peter J., Wilton, Daniel K., Jessen, Kristjan R.   +33 more
core   +1 more source

Regenerative Peripheral Nerve Interface (RPNI) and vascularized Denervated Muscle Targets (VDMT): a preclinical rabbit model as a translational feasibility and methodological platform

Journal of Translational Medicine
Background Regenerative Peripheral Nerve Interfaces (RPNIs) and Vascularized Denervated Muscle Targets (VDMTs) are emerging strategies for nerve regeneration and myoelectric prosthesis control.
Jorge González-Prieto, Mario Arenillas, Elisa Sanz Barbero, Ana Gutiérrez Pecharromán, José Daniel Muñoz, Eduardo Alonso, María del Carmen Morillo, Lara Cristóbal, Romano Giannetti, Andrés A. Maldonado   +9 more
doaj   +1 more source

Reliability of the L3 Transverse Process as a Landmark for Lumbar Spine Enumeration Across Different Vertebral Segmentation Patterns: A Retrospective CT Study

Diagnostics
Background/Objectives: Vertebral numbering on limited lumbosacral imaging is difficult when the thoracic or lumbar count varies. The L3 transverse process has been proposed as a landmark because it is often the longest, but this has not been tested ...
Jakub Jankowski, Natalia Maślanek, Marcin Glin, Marcin Jasiewicz, Agnieszka Pawełczyk, Michał Polguj, Maciej Radek   +6 more
doaj   +1 more source

REGENERATION OF PERIPHERAL NERVES [PDF]

The Journal OF Nervous and Mental Disease, 1922
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openaire   +2 more sources

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Unmasking of latent synaptic connections in the cortex of the rat, elicited by a facial nerve transection [PDF]

, 2001
Peripheral nerve injury elicits plastic changes in the cortex, resulting in reorganization of the somatotopic representation maps. These processes begin within minutes after nerve injury, and last for weeks.
Toldi, József, Toldi József, Farkas, Tamás, Farkas Tamás   +3 more
core   +1 more source