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Peripheral Nerve Conduit: Materials and Structures
ACS Chemical Neuroscience, 2019Peripheral nerve injuries (PNIs) are the most common injury types to affect the nervous system. Restoration of nerve function after PNI is a challenging medical issue. Extended gaps in transected peripheral nerves are only repaired using autologous nerve
Amitava Bhattacharyya +2 more
exaly +2 more sources
Advanced Healthcare Materials, 2022
Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice. Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair ...
Peng-Peng Deng +4 more
semanticscholar +1 more source
Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice. Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve repair ...
Peng-Peng Deng +4 more
semanticscholar +1 more source
Biomaterials, 2021
Mechanistic understanding of the topological cues delivered by biomaterials in promotion of oriented tissue regeneration (e.g., peripheral nerve regrowth) remains largely elusive.
Xian-Hao Dong +12 more
semanticscholar +1 more source
Mechanistic understanding of the topological cues delivered by biomaterials in promotion of oriented tissue regeneration (e.g., peripheral nerve regrowth) remains largely elusive.
Xian-Hao Dong +12 more
semanticscholar +1 more source
Annual Review of Neuroscience, 1990
Schwann cell basal laminae were demonstrated to serve as efficient conduits for the growth of regenerating axons in frozen nerve grafts, and in in situ freezing experiments. Regenerating axonal sprouts usually emanated from the first node of Ranvier proximal to the site of damage, and grew out along the inner surface of the basal lamina.
J W, Fawcett, R J, Keynes
openaire +4 more sources
Schwann cell basal laminae were demonstrated to serve as efficient conduits for the growth of regenerating axons in frozen nerve grafts, and in in situ freezing experiments. Regenerating axonal sprouts usually emanated from the first node of Ranvier proximal to the site of damage, and grew out along the inner surface of the basal lamina.
J W, Fawcett, R J, Keynes
openaire +4 more sources
2016
In order to understand peripheral nerve dysfunction, and to follow neuronal regeneration, basic sciences of the peripheral nerve should be understood completely. A surgeon who operates on "nerves" uses this knowledge, especially the organization of the peripheral nerve, in nerve reconstructions.
Gürsel Leblebicioğlu, A. +4 more
openaire +1 more source
In order to understand peripheral nerve dysfunction, and to follow neuronal regeneration, basic sciences of the peripheral nerve should be understood completely. A surgeon who operates on "nerves" uses this knowledge, especially the organization of the peripheral nerve, in nerve reconstructions.
Gürsel Leblebicioğlu, A. +4 more
openaire +1 more source
International Rehabilitation Medicine, 1981
The neuron is remarkable as a cell with a prolonged process, the axon. Various substances and organelles are transported up and down the axon. Axotomy profoundly affects this axonal transport. The proximal stump of the axon seals off and organelles accumulate. Terminal sprouts appear and move towards the distal stump.
K, Kristensson, T, Olsson
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The neuron is remarkable as a cell with a prolonged process, the axon. Various substances and organelles are transported up and down the axon. Axotomy profoundly affects this axonal transport. The proximal stump of the axon seals off and organelles accumulate. Terminal sprouts appear and move towards the distal stump.
K, Kristensson, T, Olsson
openaire +2 more sources
Advances in Materials
Nerve guidance conduits (NGCs) are considered as promising treatment strategy and frontier trend for peripheral nerve regeneration, while their therapeutic outcomes are limited by the lack of controllable drug delivery and available physicochemical cues.
Dongyu Xu +8 more
semanticscholar +1 more source
Nerve guidance conduits (NGCs) are considered as promising treatment strategy and frontier trend for peripheral nerve regeneration, while their therapeutic outcomes are limited by the lack of controllable drug delivery and available physicochemical cues.
Dongyu Xu +8 more
semanticscholar +1 more source
Stimulation of the Peripheral Nerve and Peripheral Nerve Field
2012Neuromodulation by stimulation is most likely active by changing the balance in excitatory and inhibitory fibers based on the theory of Melzak and Wall. Since its introduction, neuromodulation strategies have progressively been advancing into the periphery.
Jason E. Pope +3 more
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Microsurgery of Peripheral Nerves
Hand, 1973AbstractDevelopment of microsurgical techniques represents a major advance in the surgery of peripheral nerves. The operating microscope makes it possible to evaluate the severity of trauma to nerve tissue more accurately than other methods. Microsurgery has made it possible to perform atraumatic interfascicular dissection in operations for various ...
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ACS Nano, 2020
Repairing peripheral nerve injury, especially long-range defects of thick nerves, is a great challenge in the clinic due to its limited regeneration capability. Most FDA-approved nerve guidance conduits with large hollow lumen are only suitable for short
Jing Wang +7 more
semanticscholar +1 more source
Repairing peripheral nerve injury, especially long-range defects of thick nerves, is a great challenge in the clinic due to its limited regeneration capability. Most FDA-approved nerve guidance conduits with large hollow lumen are only suitable for short
Jing Wang +7 more
semanticscholar +1 more source