Results 311 to 320 of about 2,431,925 (362)

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Restoring Motor Function in Long-Term Paralyzed Muscles: Insights from Experimental and Clinical Evidence on Peripheral Nerve Reconstruction

Brain and Spine
Shimon Rochkind
doaj   +1 more source

Enhancing peripheral nerve regeneration through NaOH-based decellularization of human nerve tissue. [PDF]

Bioeng Transl Med
Kim S, Park SH, Mun J, Jung SW, Lee WJ, Lee DW, Lee KW.   +6 more
europepmc   +1 more source

The Effect of the Crustastun™ on Nerve Activity in Two Commercially Important Decapod Crustaceans: the Edible Brown Cancer Pagurus and the European Lobster Homarus Gammarus. [PDF]

, 2012
Neil, D.
core  

Polydopamine Coupled Nt3 Derived Oriented Conductive Scaffolds with Immunomodulatory Properties Accelerates Peripheral Nerve Regeneration

Ziyuan Yang, Xiaokun Chen, Jihai Xu, Jiahua Zhou, Feng Qin, Xueyuan Li, Miao Yu, Ming Li, Yanhua Wang, Xin Wang   +9 more
openalex   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

[State-of-the-art in peripheral nerve injury diagnosis and therapy]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Sun J, Chen L.
europepmc   +1 more source

Enhancing Tactile Feedback in Prosthetics: A Review of Transcutaneous Electrical Stimulation, Cortical Stimulation, and Peripheral Nerve Stimulation Approaches

Sihan Lin
openalex   +2 more sources

Conductive Chitosan-Graphene Oxide Scaffold with Applications in Peripheral Nerve Tissue Engineering. [PDF]

Polymers (Basel)
Lazăr AI, Șelaru A, Croitoru AM, Motelica L, Oprea OC, Trușcă RD, Ficai D, Văireanu DI, Ficai A, Dinescu S.   +9 more
europepmc   +1 more source