Results 81 to 90 of about 674,461 (357)

The potential benefit of artificial intelligence regarding clinical decision-making in the treatment of wrist trauma patients

Journal of Orthopaedic Surgery and Research
Purpose The implementation of artificial intelligence (AI) in health care is gaining popularity. Many publications describe powerful AI-enabled algorithms.
Marco Keller, Meret Rohner, Philipp Honigmann   +2 more
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Interest in computer-assisted surgery on the glenoid implant positioning in the context of navigated or planned total shoulder arthroplasties

JSES International
Background: Three-dimensional planning and intraoperative navigation are beneficial for glenoid implant positioning in total shoulder arthroplasty (TSA). The respective benefits of these two techniques are still being evaluated. The aim of this study was
Yannis Yahiaoui, MD, Cyril Lazerges, MD, MSc, Michel Chammas, MD, PhD, Bertrand Coulet, MD, PhD   +3 more
doaj   +1 more source

Ficus carica L. Attenuates Denervated Skeletal Muscle Atrophy via PPARα/NF-κB Pathway

Frontiers in Physiology, 2020
Treatment options for denervated skeletal muscle atrophy are limited, in part because the underlying molecular mechanisms are not well understood. Unlike previous transcriptomics studies conducted in rodent models of peripheral nerve injury, in the ...
Junxi Dai, Junxi Dai, Junxi Dai, Yaoxian Xiang, Yaoxian Xiang, Yaoxian Xiang, Da Fu, Lei Xu, Lei Xu, Lei Xu, Junjian Jiang, Junjian Jiang, Junjian Jiang, Jianguang Xu, Jianguang Xu, Jianguang Xu, Jianguang Xu   +16 more
doaj   +1 more source

Ethanol Ablation of a Peripheral Nerve Sheath Tumor Presenting as a Small Bowel Obstruction. [PDF]

, 2015
Ethanol has historically been used as an ablative agent for a variety of lesions. One of the more common applications of this technique is celiac plexus neurolysis; however, recent reports have suggested a role for the endoscopic alcohol ablation of a ...
Chang, Kenneth, Chen, Chien-Lin, Chin, Matthew, Lee, John, Samarasena, Jason   +4 more
core   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

The feasibility and usability of mixed reality teaching in a hospital setting based on self-reported perceptions of medical students

BMC Medical Education
Background Clinical teaching during encounters with real patients lies at the heart of medical education. Mixed reality (MR) using a Microsoft HoloLens 2 (HL2) offers the potential to address several challenges: including enabling remote learning ...
Michael Johnston, Megan O’Mahony, Niall O’Brien, Murray Connolly, Gabriella Iohom, Mohsin Kamal, Ahmed Shehata, George Shorten   +7 more
doaj   +1 more source

Intracellular localisation of mTHPC and effect of photodynamic therapy in cells of the mammalian peripheral nervous system [PDF]

, 2007
Fewer nerve-related side effects have been noted after treating head and neck cancer with photodynamic therapy (PDT) compared to conventional cancer therapy. Our aim is to investigate the biological basis for any such nerve-sparing effect.
MacRobert, A. J., Phillips, J. B., Wright, K. E.   +2 more
core  

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. [PDF]

, 2020
Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Basbaum, Allan I, Braz, Joao M, Guan, Zhonghui, Hamel, Katherine A, Leff, Jacqueline, Liu, Hongju, Morvan, Maelig G, Yu, Stephen, Yu, Xiaobing   +8 more
core   +1 more source

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter, Niedermeier, W., Schneider, Uwe   +2 more
core   +1 more source