Results 91 to 100 of about 674,907 (364)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

The feasibility and usability of mixed reality teaching in a hospital setting based on self-reported perceptions of medical students

BMC Medical Education
Background Clinical teaching during encounters with real patients lies at the heart of medical education. Mixed reality (MR) using a Microsoft HoloLens 2 (HL2) offers the potential to address several challenges: including enabling remote learning ...
Michael Johnston, Megan O’Mahony, Niall O’Brien, Murray Connolly, Gabriella Iohom, Mohsin Kamal, Ahmed Shehata, George Shorten   +7 more
doaj   +1 more source

Interest in computer-assisted surgery on the glenoid implant positioning in the context of navigated or planned total shoulder arthroplasties

JSES International
Background: Three-dimensional planning and intraoperative navigation are beneficial for glenoid implant positioning in total shoulder arthroplasty (TSA). The respective benefits of these two techniques are still being evaluated. The aim of this study was
Yannis Yahiaoui, MD, Cyril Lazerges, MD, MSc, Michel Chammas, MD, PhD, Bertrand Coulet, MD, PhD   +3 more
doaj   +1 more source

Decision letter for "Pre‐clinical study of Peripheral Nerve Regeneration using Nerve Guidance Conduits based on Polyhydroxyalkanaotes"

, 2021

openalex   +1 more source

Correction to “Imaging in gynecological disease (26): clinical and ultrasound characteristics of benign retroperitoneal pelvic peripheral‐nerve‐sheath tumors” [PDF]

, 2023

openalex   +1 more source

Intracellular localisation of mTHPC and effect of photodynamic therapy in cells of the mammalian peripheral nervous system [PDF]

, 2007
Fewer nerve-related side effects have been noted after treating head and neck cancer with photodynamic therapy (PDT) compared to conventional cancer therapy. Our aim is to investigate the biological basis for any such nerve-sparing effect.
MacRobert, A. J., Phillips, J. B., Wright, K. E.   +2 more
core  

Automated tracing of myelinated axons and detection of the nodes of Ranvier in serial images of peripheral nerves [PDF]

, 2015
The development of realistic neuroanatomical models of peripheral nerves for simulation purposes requires the reconstruction of the morphology of the myelinated fibres in the nerve, including their nodes of Ranvier.
Andres, Andriyenko, Auer, Berclaz, Breiman, Cardona, da Silva, Denk, Feria-Velasco, Frangi, Funke, Funke, Gierthmuehlen, Helmstaedter, Huelsenbeck, Hunter, Karnovsky, Kim, Kreshuk, Kuhn, Li, Li, Lindeberg, Liu, Lou, More, Novas, Nunez-Iglesias, Plachta, Plachta, Ramachandran, Romero, Sato, Schindelin, Schultze, Smith, Sommer, Vazquez-Reina, Vita, Yang, Zhang   +40 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Facial Nerve Axotomy in Mice: A Model to Study Motoneuron Response to Injury [PDF]

, 2015
The goal of this surgical protocol is to expose the facial nerve, which innervates the facial musculature, at its exit from the stylomastoid foramen and either cut or crush it to induce peripheral nerve injury.
Batka, Richard J., Haulcomb, Melissa M., Jones, Kathryn J., Mesnard-Hoaglin, Nichole A., Miller, Whitney M., Olmstead, Deborah N.   +5 more
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source