Results 81 to 90 of about 2,424,061 (363)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter

, 2004
Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Coffin, RS, Hossain-Ibrahim Kismet, Mason, MRJ, Lieberman AR, Lieberman, AR, Mason Matthew RJ, Hossain-Ibrahim, K, David Hunt, Winterbottom, J, Anderson, PN, Hunt David, AR Lieberman, Kismet Hossain-Ibrahim, Anderson PN, Coffin Robert S, Hunt, D, PN Anderson, Matthew RJ Mason, Robert S Coffin, Winterbottom Julia, Julia Winterbottom   +20 more
core   +1 more source

Early diagnosis of neuropathy in leprosy: comparing diagnostic tests in a large prospective study (the INFIR Cohort Study) [PDF]

, 2008
BackgroundLeprosy is the most frequent treatable neuromuscular disease. Yet, every year, thousands of patients develop permanent peripheral nerve damage as a result of leprosy.
Wilder-Smith, Einar P, Pramila Barkataki, van Brakel, Wim H, van Brakel Wim H., Wim H van Brakel, Diana N J Lockwood, Einar P Wilder-Smith, Nicholls Peter G., Peter G Nicholls, Wilder-Smith Einar P., Nicholls, Peter G, Lockwood Diana N. J., Das Loretta, INFIR Study Group, Nicholls, Peter G., Lockwood, Diana N.J, Das, Loretta, Barkataki, Pramila, Barkataki Pramila, van Brakel, W.H., Loretta Das, Wilder-Smith, Einar P., Lockwood, Diana NJ   +22 more
core   +1 more source

Total Elbow Arthroplasty and Antegrade Posterior Interosseous Flap for Infected Posttraumatic Arthritis with an Active Fistula. A Rationale for Comprehensive Treatment. Case Report

Journal of Shoulder and Elbow Arthroplasty, 2022
The indication for total elbow arthroplasty (TEA) for primary and posttraumatic elbow arthritis has increased, however, its indication after infection remains elusive.
Efraín Farías-Cisneros MD, PhD, FACS, Jorge Luis Martínez-Peniche MD, Luis Carlos Olguín-Delgado MD, Francisco Guillermo Castillo-Vázquez MD, Ranulfo Romo-Rodríguez MD, FACS, Armando Torres-Gómez MD, MSc, FACS   +5 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

A Review for the Peripheral Nerve Interface Designer.

Journal of Neuroscience Methods, 2019
Informational density and relative accessibility of the peripheral nervous system make it an attractive site for therapeutic intervention. Electrode-based electrophysiological interfaces with peripheral nerves have been under development since the 1960s ...
Christopher E. Larson, E. Meng
semanticscholar   +1 more source

Chapter 28 future perspective in peripheral nerve reconstruction.

, 2009
Nerve injuries induce severe disability and suffering for patients. Profound alterations in nerve trunks, neurons, and the central nervous system are induced rapidly after injury.
Dahlin, Lars, Martin Kanje, Lars Dahlin, Charlotta Lindwall, Lindwall, Charlotta, Fredrik Johansson, Kanje, Martin, Lindwall, Charlotta,, Johansson, Fredrik   +8 more
core   +1 more source

All-Endoscopic Resection of an Infraclavicular Brachial Plexus Schwannoma: Surgical Technique

Arthroscopy Techniques, 2018
Due to recent progress in shoulder arthroscopy, all-endoscopic brachial plexus (BP) dissection has progressively become a standardized procedure. Based on previously described techniques, we present an additional neurological procedure that may be ...
Thibault Lafosse, M.D., Malo Le Hanneur, M.D., Ion-Andrei Popescu, M.D., Thomas Bihel, M.D., Emmanuel Masmejean, M.D., Ph.D., Laurent Lafosse, M.D.   +5 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Niedermeier, W., Schneider, Uwe, Grafe, Peter   +2 more
core