Results 101 to 110 of about 191,191 (308)

Gene therapy targeting SARM1 blocks pathological axon degeneration in mice [PDF]

open access: yes, 2019
Axonal degeneration (AxD) following nerve injury, chemotherapy, and in several neurological disorders is an active process driven by SARM1, an injury-activated NADase.
DiAntonio, Aaron   +8 more
core   +1 more source

Trigeminal neuralgia - diagnosis and treatment [PDF]

open access: yes, 2017
Introduction Trigeminal neuralgia (TN) is characterized by touch-evoked unilateral brief shock-like paroxysmal pain in one or more divisions of the trigeminal nerve. In addition to the paroxysmal pain, some patients also have continuous pain.
Bendtsen, Lars   +3 more
core   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput   +5 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Ultrasound-Guided Supraorbital Nerve Block For Orbital Chronic Cancer Pain - A Case Report

open access: yesJAI (Jurnal Anestesiologi Indonesia)
Background: Many individuals with cancer suffer from pain symptom, typically ranging from moderate to severe levels. Multimodal approach has been used widely to manage the cancer pain.
Mochamat Mochamat
doaj   +1 more source

The comparative study of two techniques of lumbar plexus block by anterior and posterior approach for lower limb surgery

open access: yesIndian Journal of Pain, 2017
Background: Lower extremity peripheral nerve blocks (PNBs) have been traditionally less employed compared to other forms of regional anesthesia. The advent of peripheral nerve stimulator and ultrasonography, complications associated with neuraxial ...
Milon Vasant Mitragotri   +4 more
doaj   +1 more source

Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]

open access: yes, 1991
The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
DYCK P. J.   +11 more
core   +1 more source

Polymer‐Incorporated Mechanically Compliant Carbon Nanotube Microelectrode Arrays for Multichannel Neural Signal Recording

open access: yesAdvanced Functional Materials, EarlyView.
This work presents a soft microelectrode array based on vertically aligned carbon nanotube (CNT) forests, combining high conductivity with mechanical softness. A densification process and air‐pressure‐assisted flexibilization improve structural integrity, ensuring stable insertion and reduced inflammation.
Hyeonhee Roh   +8 more
wiley   +1 more source

Evaluation of the effect of intraoperative tropisetron on postoperative rebound pain after brachial plexus block: a randomized controlled trial

open access: yesPAIN Reports
. Introduction:. Postoperative rebound pain after peripheral nerve block increases patient suffering and delays recovery after surgery. Objectives:.
Junli Liu   +6 more
doaj   +1 more source

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