Results 211 to 220 of about 286,657 (266)

Injectable chitosan-based hydrogel via in situ gelation modulates the inflammatory microenvironment and facilitates minimally invasive repair of peripheral nerve injury. [PDF]

Mater Today Bio
Zhai Y, Guan X, Lu C, Sun R, Qian Y, Li Y, Zhang K, Wang X, Xu L, Yin X, Guo S, Wu J, Fan C.   +12 more
europepmc   +1 more source

A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster

Animal Models and Experimental Medicine, EarlyView.
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang, Tao Ding, Wanjun Peng, Jie Kong, Xiaoyue Tang, Jiyu Xu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Yizhuo Tian, Huilan Yang, Yehong Yang, Yue Wu, Xiaoyan Liu, Jiangfeng Liu, Juntao Yang   +15 more
wiley   +1 more source

The dual roles of chemokines in peripheral nerve injury and repair. [PDF]

Inflamm Regen
Wang F, Zhao C, Jing Z, Wang Q, Li M, Lu B, Huo A, Liang W, Hu W, Fu X.   +9 more
europepmc   +1 more source

A novel mouse model simulating C5 palsy after cervical surgery

Animal Models and Experimental Medicine, EarlyView.
This study establishes a reliable mouse model of permanent C5 palsy (post‐laminectomy complication) via dorsal approach, selectively severing the C5 anterior nerve root while preserving the posterior root through partial C4 and C5 laminectomy. The model successfully replicates clinical C5P features—flaccid shoulder paralysis, electrophysiological ...
Chenpei Xu, Xianghe Wang, Mingjie Zhou, Chuxiang Chen, Tingzheng Jiang, Fei Wang, Kaixiang Yang, Hongli Wang, Su Jiang   +8 more
wiley   +1 more source

A bioengineered vinpocetine- and menstrual blood stem cell-loaded neural conduit for treating peripheral nerve injury after bone fractures. [PDF]

J Mater Sci Mater Med
Li G, Yan Y, Hou Y, Zhao G, Wang X, Cui M, Du H.   +6 more
europepmc   +1 more source

Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia [PDF]

, 2019
Carlin, Dan, Cavalli, Valeria, Ewan, Eric E, Halevi, Alexandra E, Moore, Amy M   +4 more
core   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Peripheral nerve injury mediated by JEV strain NX1889 infection and impairment of Schwann cells. [PDF]

PLoS Negl Trop Dis
Yang L, Yuan Y, Yin Q, Li X, Kang X, Cui Q, Wang G, Yang H, Wang R, Yang T, Li F, Fu S, Wang H, Wang Z.   +13 more
europepmc   +1 more source

The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart

Animal Models and Experimental Medicine, EarlyView.
The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang, Haifeng Jiang, Zhen Xu, Tingyu Dong, Xiaoyi Liu, Shangxue Yan, Jiajie Kuai, Yan Chang, Wei Wei   +8 more
wiley   +1 more source

Peripheral nerve injury-induced remodeling of the tumor-associated macrophages promotes immune evasion in breast cancer. [PDF]

J Exp Clin Cancer Res
Jiang Y, Zeng W, Feng Y, Deng X, Wang J, Liu H, Gao B, Bi D, Liu Z, Yang C, Chen M, Li T, Chen H, Zhang Y, Liang L, Xu J, Deng W, Yao Z, Wu W, Lao L, Chen J, Huang P.   +21 more
europepmc   +1 more source