Results 251 to 260 of about 514,275 (310)

Gene Therapy for Peripheral Nervous System Diseases

Current Gene Therapy, 2007
Peripheral nerve diseases, also known as peripheral neuropathies, affect 15-20 million of Americans and diabetic neuropathy is the most common condition. Currently, the treatment of peripheral neuropathies is more focused on managing pain rather than providing permissive conditions for regeneration.
Thais, Federici, Nicholas, Boulis
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Neurologic Manifestations of Systemic Disease: Peripheral Nervous System

Current Treatment Options in Neurology, 2020
The impact that systemic disease has on the peripheral nervous system is vast. Polyneuropathies due to these disorders fall into broad categories including metabolic diseases, nutritional deficiencies, rheumatological diseases, infectious diseases, and malignancy-associated disorders.
Alex Dworetz, Christina Graley, Hiral Padia, Kelly G. Gwathmey   +3 more
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Immune‐mediated diseases involving central and peripheral nervous systems

European Journal of Neurology, 2022
AbstractBackground and purposeIn addition to combined central and peripheral demyelination, other immune diseases could involve both the central nervous system (CNS) and peripheral nervous system (PNS).MethodsTo identify immune‐mediated diseases responsible for symptomatic combined central/peripheral nervous system involvement (ICCPs), we conducted a ...
Aurelie Leboyan, Florence Esselin, Anne‐Laure Bascou, Claire Duflos, Ioana Ion, Mahmoud Charif, Giovanni Castelnovo, Clarisse Carra‐Dalliere, Xavier Ayrignac, Philippe Kerschen, Mohamed Chbicheb, Ludovic Nguyen, Alexandre T. J. Maria, Philippe Guilpain, Mathilde Carriere, Nicolas Menjot de Champfleur, Thierry Vincent, Alexandre Jentzer, Pierre Labauge, Jérôme J. Devaux, Guillaume Taieb   +20 more
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Peripheral Nervous System (PNS) Myelin Diseases

Cold Spring Harbor Perspectives in Biology
This is a review of inherited and acquired causes of human demyelinating neuropathies and a subset of disorders that affect axon-Schwann cell interactions. Nearly all inherited demyelinating neuropathies are caused by mutations in genes that are expressed by myelinating Schwann cells, affecting diverse functions in a cell-autonomous manner.
Steven S, Scherer, John, Svaren
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Lyme disease and the peripheral nervous system

Muscle & Nerve, 2003
AbstractLyme disease, the multisystem infectious disease caused by the tick‐borne spirochete Borrelia burgdorferi, causes a broad variety of peripheral nerve disorders, including single or multiple cranial neuropathies, painful radiculopathies, and diffuse polyneuropathies. Virtually all appear to be varying manifestations of a mononeuropathy multiplex.
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Central and Peripheral Nervous System Diseases

2007
Immune diseases of the central and peripheral nervous system constitute an heterogeneous group of disorders which share a significative implication of the immune system in pathophysiology. Multiple sclerosis (MS), Guillain Barre syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) are considered of autoimmune origin, with an ...
Dorothée Chabas, Isabelle Cournu-Rebeix, Bertrand Fontaine   +2 more
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Diseases of the Peripheral Nervous System

1999
The oral cavity and the surrounding facial tissue maybe part of the clinical spectrum of different neurological conditions. Most of these disorders involve the 7th, facial, and the 12th, hypoglossal, cranial nerves.
L. Bianchi, M. Argenta, G. Nini
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Peripheral nervous system disease in Systemic Lupus Erythematosus

2019
Objectives: In a multi-ethnic/racial, prospective SLE inception cohort, to determine the frequency, clinical characteristics, associations and outcomes in different types of peripheral nervous system (PNS) disease. Methods: Patients were evaluated annually for 19 neuropsychiatric (NP) events including seven types of PNS disease.
Hanly, John, Li, Qiuju, Su, Li, Urowitz, Murray, Gordon, Caroline, Farewell, Vern   +5 more
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Early peripheral nervous system manifestations of infantile Krabbe disease

Pediatric Neurology, 2003
Early infantile Krabbe disease is relatively frequent in the Muslim-Arab population in Israel. It can be easily diagnosed when it presents with the classic clinical picture characterized by central nervous system manifestations of spasticity, irritability, motor regression and seizures associated with a positive family history.
Isabelle, Korn-Lubetzki, Talia, Dor-Wollman, Dov, Soffer, Annick, Raas-Rothschild, Haggit, Hurvitz, Yoram, Nevo   +5 more
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Peripheral Nervous System Damage in Experimental Chronic Chagas' Disease

The American Journal of Tropical Medicine and Hygiene, 1987
Electromyographic and histopathologic studies were performed in Rockland mice chronically infected with CA-I Trypanosoma cruzi strain. At 4 months post-infection the emg failed to show spontaneous activity, but a diminished interference pattern was detected in half of the infected group, while mean motor unit potential amplitude and duration were ...
S M, González Cappa, O P, Sanz, L A, Muller, H A, Molina, J, Fernández, M T, Rimoldi, R E, Sica   +6 more
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