Results 1 to 10 of about 18,217,681 (301)

Peripheral nervous system involvement in systemic amyloidosis [PDF]

Неврология, нейропсихиатрия, психосоматика, 2018
Peripheral nervous system involvement may be a main manifestation of systemic amyloidosis or occur in the later stages of the disease in the presence of multiple organ pathology.
E. I. Safiulina, O. E. Zinovyeva, V. V. Rameev, L. V. Kozlovskaya-Lysenko   +3 more
doaj   +2 more sources

Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of anticoagulants

Journal of Neuroinflammation, 2019
Background Macrophage-derived high mobility group box 1 (HMGB1), a damage-associated molecular pattern (DAMP) protein, plays a key role in the development of chemotherapy-induced peripheral neuropathy (CIPN) caused by paclitaxel in rodents.
Maho Tsubota, Ryotaro Fukuda, Yusuke Hayashi, Takaya Miyazaki, Shin Ueda, Rika Yamashita, Nene Koike, Fumiko Sekiguchi, Hidenori Wake, Shuji Wakatsuki, Yuka Ujiie, Toshiyuki Araki, Masahiro Nishibori, Atsufumi Kawabata   +13 more
doaj   +1 more source

Case Report: Postpartum diagnosis and microsurgical management of a cervicothoracic intramedullary spinal ependymoma clinically manifesting during the third trimester of pregnancy

Frontiers in Oncology
BackgroundIntramedullary spinal cord ependymomas are the most common intramedullary tumours in adults. However, clinical manifestation during pregnancy is exceptionally rare, and diagnosis may be delayed because pain, sensory disturbances, and muscle ...
Talgat T. Kerimbayev, Daryn Borangaliyev, Azamat Abenov, Daniyar K. Zhamoldin, Galymzhan Kadirbekov, Zhandos Tuigynov, Yergen Kenzhegulov, Viktor G. Aleinikov, Berik Zhetpisbayev, Yermek Urunbayev, Nurzhan Abishev, Meirzhan Oshayev, Aisa Z. Nurperisov, Zhanibek Baiturlin, Makar Solodovnikov, Serik K. Akshulakov   +15 more
doaj   +1 more source

Collagen VI in healthy and diseased nervous system

Disease Models & Mechanisms, 2018
Collagen VI is a major extracellular matrix protein exerting a number of functions in different tissues, spanning from biomechanical to regulatory signals in the cell survival processes, and playing key roles in maintaining the stemness or determining ...
Ilaria Gregorio, Paola Braghetta, Paolo Bonaldo, Matilde Cescon   +3 more
doaj   +1 more source

Microglia Involvement into Acute and Chronic Brain Damage in Diabetic Rats: Impact of GLP-1RA and SGLT-2i

Frontiers in Bioscience-Landmark
Background: Acute and chronic brain damage in type 2 diabetes mellitus (DM) determines the need to investigate the neuroprotective potential of glucose-lowering drugs.
Anna Simanenkova, Oksana Fuks, Natalya Timkina, Alina Islamova, Dina Sufieva, Оlga Kirik, Dmitrii Korzhevskii, Timur Vlasov, Tatiana Karonova   +8 more
doaj   +1 more source

PERIPHERAL NERVOUS SYSTEM INVOLVEMENT IN LYMPHOPROLIFERATIVE DISORDERS

Mediterranean Journal of Hematology and Infectious Diseases, 2018
Peripheral neuropathies are a vast group of diseases with heterogeneous aetiologies, including genetic and acquired causes. Several haematological disorders may cause an impairment of the peripheral nervous system, with diverse mechanisms and variable ...
Mario Sabatelli, Luca Laurenti, Marco Luigetti   +2 more
doaj   +1 more source

Characterizing white matter hyperintensities in myotonic dystrophy type 1 through IVIM derived metrics

Scientific Reports
Myotonic dystrophy type 1 (DM1) is a genetic disease which affects multiple systems including the central nervous system. One of its key neuroimaging biomarkers are white matter hyperintensities (WMHs). The clinical relevance of WMHs remains unclear, and
Marina Di Stefano, Nivedita Agarwal, Giulia Canella, Eleonora Diella, Morena delle Fave, Giovanni Meola, Maria Grazia D’Angelo, Denis Peruzzo   +7 more
doaj   +1 more source

Peripheral nervous system in limited systemic sclerosis

Reumatismo, 2011
Objectives. PNS is involved in Systemic Sclerosis (SSc) since the earliest phases. Our aim is to perform an ultrastructural study on skin PNS fibers in SSc. Methods.
D. Melchiorre, S. Guiducci, S. Generini, A. Franca Milia, D. Nosi, A. Tani, L. Ibba Manneschi, A. Del Rosso, A. Pignone, M. Matucci Cerinic   +9 more
doaj   +1 more source

Living with Duchenne Muscular Dystrophy Beyond the Physical Implications: Cognitive Features, Psychopathology Aspects, and Psychosocial Resources—A Narrative Review

Brain Sciences
Background/Objectives: Duchenne muscular dystrophy (DMD) is often discussed in the literature with regard to physical impairments. This narrative review aims to show that living with DMD involves psychological, psychosocial, and cognitive aspects in ...
Federica Tizzoni, Giulia Canella, Antonella Delle Fave, Daniele Di Lernia, Maria Luisa Lorusso, Maria Nobile, Maria Grazia D’Angelo   +6 more
doaj   +1 more source

Quantitative thermal sensory testing and sympathetic skin response in primary Restless legs syndrome - A prospective study on 57 Indian patients

Annals of Indian Academy of Neurology, 2012
Patients with restless leg syndrome present with sensory symptoms similar to peripheral neuropathy. While there is evidence of abnormalities of dopaminergic pathways, the peripheral nervous system has been studied infrequently.
Garima Shukla, Vinay Goyal, Achal Srivastava, Madhuri Behari   +3 more
doaj   +1 more source