Results 31 to 40 of about 19,186,071 (258)

Neuromuscular junction formation by compartmentalized culture using human iPS cell-derived motor neurons and skeletal muscle cells

Frontiers in Neural Circuits
The neuromuscular junction (NMJ) is a synapse that connects the nerve terminal of a motor neuron to a skeletal muscle fiber. The mechanisms underlying NMJ formation have been elucidated primarily through studies in animal models.
Masayoshi Kamon, Moe Yamashita, Moe Yamashita, SokeLee Siew, Shuji Wakatsuki, Toshiyuki Araki, Toshiyuki Araki   +6 more
doaj   +1 more source

Peripheral nervous system: A promising source of neuronal progenitors for central nervous system repair

Frontiers in Neuroscience, 2022
With a steadily aging population there is an increasing prevalence of neurological disorders. Given the lack of effective treatment strategies and a limited ability for the central nervous system (CNS) to regenerate endogenously, there is a critical need
Jessica L. Mueller, Rhian Stavely, Ryo Hotta, Allan M. Goldstein   +3 more
doaj   +1 more source

Peripheral nervous system involvement in lymphomas

, 2018
The peripheral nervous system may be involved at any stage in the course of lymphoproliferative diseases. The different underlying mechanisms include neurotoxicity secondary to chemotherapy, direct nerve infiltration (neurolymphomatosis), infections ...
Cavallaro, T., Visentin, Andrea, Visentin, A., Campagnolo, Marta, Campagnolo, M., Manara, R., Marta Campagnolo, Briani, C., Salvalaggio, Alessandro, Chiara Briani, Ferrari, Sergio, Salvalaggio, A., Manara, Renzo, Alessandro Salvalaggio, Renzo Manara, Roberto Gasparotti, Briani, Chiara, Andrea Visentin, Francesco Piazza, Gasparotti, R., Ferrari, S., Tiziana Cavallaro, Cavallaro, Tiziana, Sergio Ferrari, Gasparotti, Roberto, Piazza, Francesco, Piazza, F.   +26 more
core   +1 more source

Nervous system: Peripheral neuroblastic tumours (Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma) [PDF]

, 1998
Review on Nervous system: Peripheral neuroblastic tumours (Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma), with data on clinics, and the genes ...
Couturier, J, Satgé, D
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Role for Drug Transporters in Chemotherapy‐Induced Peripheral Neuropathy

Clinical and Translational Science, 2021
Chemotherapy‐induced peripheral neuropathy (CIPN) is a common and dose‐limiting toxicity to widely used chemotherapeutics. Although the exact molecular mechanism of chemotherapy‐induced peripheral neuropathy remains elusive, there is consensus that it is
Tore B. Stage, Shuiying Hu, Alex Sparreboom, Deanna L. Kroetz   +3 more
doaj   +1 more source

Nervous system: Peripheral neuroblastic tumours (Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma) [PDF]

, 2009
Review on Nervous system: Peripheral neuroblastic tumours (Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma), with data on clinics, and the genes ...
Speleman, F, Ambros, IM, Ambros, PF
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System [PDF]

, 2019
In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Federica Miressi, Laurent Magy, Franck G. Sturtz, Pierre Antoine Faye, Frédéric Favreau, Claire Demiot, François Poumeaud, Anne Sophie Lia   +7 more
core   +2 more sources

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology
Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression.
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
doaj   +1 more source