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Lyme disease and the peripheral nervous system

Muscle & Nerve, 2003
AbstractLyme disease, the multisystem infectious disease caused by the tick‐borne spirochete Borrelia burgdorferi, causes a broad variety of peripheral nerve disorders, including single or multiple cranial neuropathies, painful radiculopathies, and diffuse polyneuropathies. Virtually all appear to be varying manifestations of a mononeuropathy multiplex.
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Involvement of peripheral nervous system in juvenile Parkinson's disease

Acta Neurologica Scandinavica, 2009
We evaluated, by using electrophysiological techniques, 29 patients with juvenile Parkinson's disease (JP), who had no known causes or clinical signs of neuropathy. Electromyographic evidence of chronic partial denervation with reinnervation was observed in nine patients (34.6%).
Arun B Taly, Uday B. Muthane
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Central and Peripheral Nervous System Diseases

2007
Immune diseases of the central and peripheral nervous system constitute an heterogeneous group of disorders which share a significative implication of the immune system in pathophysiology. Multiple sclerosis (MS), Guillain Barre syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) are considered of autoimmune origin, with an ...
Dorothée Chabas   +2 more
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Immune Diseases of the Peripheral Nervous System

1983
When considering the immunological mechanisms involved in the pathogenesis of any disease of the peripheral nervous system (PNS) three major questions must be asked: 1. What is the target antigen? 2. What causes the immune damage? 3. What triggers the immune response?
C. C. A. Bernard, I. M. Roberts
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IgG4-related disease of the central and peripheral nervous systems

The Lancet Neurology, 2018
IgG4-related disease can involve nearly any organ system, including the central and peripheral nervous systems. The pathology findings are consistent from organ to organ, but careful clinicopathological correlation is necessary to establish the diagnosis.
Nagagopal Venna   +2 more
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Paraneoplastic Diseases of the Peripheral Nervous System

2016
Peripheral nervous system involvement is the most commonly observed condition in patients with paraneoplastic neurological syndromes (PNS), and its clinical manifestations are highly heterogeneous. The peripheral nervous system can be variously involved, but the most frequently affected sites are the dorsal ganglia and presynaptic nerve endings of the ...
Anna Grisold   +2 more
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T lymphocyte autoimmunity in peripheral nervous system autoimmune disease

Agents and Actions, 1986
Autoaggressive T cells specific for the PNS myelin P2 protein play a central role in the initiation of EAN in the Lewis rat, although there is as yet no direct experimental evidence that the T cells can themselves mediate demyelination in vivo. However, the striking similarities in the pathogenesis of EAN and the Guillain-Barre syndrome suggest that T ...
Richard Meyermann   +2 more
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Peripheral Nervous System (PNS) Myelin Diseases

Cold Spring Harbor Perspectives in Biology
This is a review of inherited and acquired causes of human demyelinating neuropathies and a subset of disorders that affect axon-Schwann cell interactions. Nearly all inherited demyelinating neuropathies are caused by mutations in genes that are expressed by myelinating Schwann cells, affecting diverse functions in a cell-autonomous manner.
Steven S, Scherer, John, Svaren
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B vitamins and diseases of the peripheral nervous system

S.S. Korsakov Journal of Neurology and Psychiatry
Various diseases of the peripheral nervous system are associated with metabolic disorders of B vitamins. A lack of neurotropic vitamins, which began in the early stages of the development of a bacterial disease, led to its more rapid development. The article analyzes data on B vitamin deficiency in the pathogenesis of the most dangerous diseases of the
P.R. Kamchatnov   +4 more
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Peripheral nervous system diseases of surgical interest

2001
Injuries to the peripheral nervous system that hold surgical interest are: traumatic and iatrogenic lesions, entrapment and canicular injuries, and tumoral injuries.
Pierpaolo Lunardi   +2 more
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