Results 61 to 70 of about 419,855 (353)

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut, Romain Marignier, Mikael Cohen, Jeanne Benoit, Cassandre Landes‐Chateau, Elisabeth Maillart, Marion Cremoni, Barbara Seitz‐Polski, Anne‐Laurie Pinto, Pauline Dumez, Jérôme Honnorat, Christine Lebrun‐Frenay   +11 more
wiley   +1 more source

Clinical characteristics of peripheral nerve hyperexcitability syndrome

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To summarize the clinical characteristics of peripheral nerve hyperexcitability syndrome (PNHS). Methods and Results Ten patients with PNHS were admitted to He'nan Provincial People's Hospital from October 2018 to April 2022, with the clinical ...
MEI Wen-li, LI Liu-yi, FENG Shu-yan, ZHANG Jie-wen   +3 more
doaj   +1 more source

PERIPHERAL NERVOUS SYSTEM INVOLVEMENT IN LYMPHOPROLIFERATIVE DISORDERS

Mediterranean Journal of Hematology and Infectious Diseases, 2018
Peripheral neuropathies are a vast group of diseases with heterogeneous aetiologies, including genetic and acquired causes. Several haematological disorders may cause an impairment of the peripheral nervous system, with diverse mechanisms and variable ...
Mario Sabatelli, Luca Laurenti, Marco Luigetti   +2 more
doaj   +1 more source

Production and characterization of monoclonal antibodies to the extracellular domain of PO [PDF]

, 1993
Seven monoclonal antibodies were raised against the immunoglobulin-like extracellular domain of PO (POED), the major protein of peripheral nervous system myelin. Mice were immunized with purified recombinant rat PO-ED.
Archelos, JJ, Hartung, H.-P., Linington, C., Roggenbuck, K., Schneider-Schaulies, Jürgen, Toyka, KV   +5 more
core  

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Peripheral nervous system involvement in Parkinson's disease: Evidence and controversies

Parkinsonism & Related Disorders, 2014
In recent years, non-motor features of Parkinson's disease (PD) have received increasing attention and PD is currently considered a systemic rather than a pure basal ganglia disorder. Among the systemic features, peripheral neuropathy (PN) is a recent acquisition since the first case-control study reporting increased frequency of PN in PD dates back to
Comi, C., Magistrelli, Oggioni, L., Carecchio, G. D., Fleetwood, M., Cantello, T., Mancini, R., ANTONINI, ANGELO   +7 more
openaire   +6 more sources

Clinical and electrodiagnostic findings in a cohort of 61 dogs with peripheral nervous system diseases - a retrospective study [PDF]

Pakistan Veterinary Journal, 2014
The electrodiagnostic examination provides the basis for a diagnostic workup in diseases involving nerve roots, peripheral nerves, neuromuscular junctions and muscles in humans and animals.
EG Giza, JE Nicpon and MA Wrzosek
doaj  

Nerve Biopsy in Peripheral Neuropathies: Not All Water Is under the Bridge

Brain Sciences, 2021
Sural nerve biopsy has long been a valuable diagnostic tool for the study of peripheral neuropathies, although the recent introduction of non-invasive techniques (e.g., neuroimaging techniques, skin biopsy) and advanced genetic and immunological testing ...
Marco Luigetti, Andrea Di Paolantonio
doaj   +1 more source

Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity [PDF]

, 2017
No abstract ...
Habenicht, Andreas J.R., Maffia, Pasquale, Mohanta, Sarajo, Yin, Changjun   +3 more
core   +2 more sources

Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Zhuoran Wang, Haiting Li, Xiaoping Du, Qiong Wang, Yating Zhang, Huifang Wang   +5 more
wiley   +1 more source