Results 71 to 80 of about 19,735,029 (303)

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Drugs and the autonomic nervous system [PDF]

, 2012
The nervous systems can initially be divided up into the central and peripheral nervous systems. The central nervous system is the brain and spinal cord and drugs that modify the central nervous system are considered as a subject in systematic ...
Doggrell, Sheila
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Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

A review on recent advances on nobiletin in central and peripheral nervous system diseases. [PDF]

Eur J Med Res, 2023
Pang Y, Xiong J, Wu Y, Ding W.
europepmc   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Immune‐mediated diseases involving central and peripheral nervous systems

, 2023
International audienceBackground and purpose: In addition to combined central and peripheral demyelination, other immune diseases could involve both the central nervous system (CNS) and peripheral nervous system (PNS).Methods: To identify immune-mediated
Labauge, Pierre, Philippe Guilpain, Florence Esselin, Ayrignac, Xavier, Charif, Mahmoud, Aurelie Leboyan, Mahmoud Charif, Kerschen, Philippe, Claire Duflos, Leboyan, Aurelie, Castelnovo, Giovanni, Alexandre Jentzer, Carra-Dalliere, Clarisse, Nguyen, Ludovic, Maria, Alexandre, Clarisse Carra‐Dalliere, Mohamed Chbicheb, Xavier Ayrignac, Pierre Labauge, Taieb, Guillaume, Ludovic Nguyen, Jérôme J. Devaux, Devaux, Jérôme J., Giovanni Castelnovo, Duflos, Claire, de Champfleur, Nicolas Menjot, Ioana Ion, Alexandre T. J. Maria, Vincent, Thierry, Esselin, Florence, Thierry Vincent, Ion, Ioana, Jentzer, Alexandre, Mathilde Carriere, Nicolas Menjot de Champfleur, Bascou, Anne‐laure, Chbicheb, Mohamed, Guillaume Taieb, Carriere, Mathilde, Guilpain, Philippe, Philippe Kerschen, Anne‐Laure Bascou   +41 more
core   +1 more source

Facial nerve palsy: incidence of different ethiologies in a tertiary ambulatory

International Archives of Otorhinolaryngology, 2009
Introduction: The ethiologic diferencial diagnostic for facial nerve paralisis is still a challenge and the literature has shown conflictive results concerning its epidemiology.
Atolini Junior, Nédio, Jorge Junior, José Jarjura, Gignon, Vinícius de Faria, Kitice, Adriano Tomio, Prado, Letícia Suriano de Almeida, Santos, Vânia Gracia Wolff   +5 more
doaj  

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Essential Clinically Applied Anatomy of the Peripheral Nervous System in the Limbs

, 2015
Essential Clinically Applied Anatomy of the Peripheral Nervous System in the Limbs is designed to combine the salient points of the anatomy of the PNS with typical pathologies affecting the nerves of the upper and lower limbs.
Rea, Paul
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