Results 181 to 190 of about 17,998,872 (270)

Clinical neuroanatomy teaching at Peking University Health Science Center: Evolution, current practice, and future direction

Anatomical Sciences Education, EarlyView.
Abstract Neuroanatomy has been considered one of the most challenging subjects in medical education, often leading to “neurophobia” and discouraging students from pursuing neurological specialties. At PKUHSC, the curriculum has evolved from a traditional, discipline‐based model to a technology‐enhanced, integrated “Nervous System” module for ...
Xuan Fang, Man Li, Xiaodan Hu, Chang Su, Shan Ye, Xianzhong Shi, Xiaomei Yang, Changman Zhou, Weiguang Zhang, Chunhua Chen   +9 more
wiley   +1 more source

Clinical Impact of Germline Multigene Sequencing in Pediatric Cohorts with a Wide Spectrum of Neoplasms. [PDF]

Int J Mol Sci
Semenova V, Zhukovskaya E, Zelenova E, Kozlova V, Krasnov G, Levashov A, Sagoyan G, Belysheva T, Kharchikov D, Suleymanova A, Ivanova N, Lozovaya A, Rubanskaya M, Gelfer S, Sharapova E, Mikhaylova S, Valiev T, Karelin A, Varfolomeeva S, Nasedkina T.   +19 more
europepmc   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Neural regulation of cancer: from synaptic integration to neuro-immune regulation. [PDF]

Cell Oncol (Dordr)
Li X, Li Y, Shi X, Wang Y, Ji S.
europepmc   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

A 13-Year Review of Non-Diffuse Large B Cell Lymphomas of the Central Nervous System at a Tertiary Hospital: A Case Series Study. [PDF]

Neuropathology
Sina N, Heyn C, Ghorab Z, Keith J.
europepmc   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Primary Intramedullary Histiocytic Sarcoma with Leptomeningeal Dissemination: Imaging, Pathologic, and Molecular Correlation. [PDF]

Diagnostics (Basel)
Kim SH, Kwon HJ, Gu MJ, Park WT.
europepmc   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Central Nervous System Embryonal Tumour With PLAGL Amplification Lacking Typical Embryonal Morphology: Diagnostic Pitfall in a Paediatric Case. [PDF]

Neuropathol Appl Neurobiol
Okuse R, Nobusawa S, Kurose A, Kamataki A, Sato Y, Sugimoto R, Suzuki H, Yanagawa N, Beppu T.   +8 more
europepmc   +1 more source