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Schwann cells in regeneration and cancer [PDF]
Frontiers in PharmacologySchwann cells are specific peripheral glial cells with remarkable plasticity following peripheral nerve injury. Injury responses stimulate c-Jun activation in Schwann cells, drive epithelial-mesenchymal transition and cellular phenotypic changes, and ...
Lan Zhang +4 more
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The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy [PDF]
Frontiers in Cellular Neuroscience, 2022 Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang +8 more
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HLA‐DR+ Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell Carcinoma [PDF]
Advanced ScienceNeural structures are widely distributed in the oral and maxillofacial region and play important roles in the progression of head and neck squamous cell carcinoma (HNSCC).
Xiaoyan Meng +7 more
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Schwann cells in the inner ear: development, disease, and regeneration [PDF]
Frontiers in Cellular NeuroscienceSchwann cells are classically known as the constituent supporting cells of the peripheral nervous system. Beyond the scope of merely myelinating axons of the more saliently known neurons, Schwann cells comprise the majority of peripheral nervous system ...
Drew J. Montigny +6 more
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Cell Transplantation, 2001 Areas of demyelination can be remyelinated by transplanting myelin-forming cells. Schwann cells are the naturally remyelinating cells of the peripheral nervous system and have a number of features that may make them attractive for cell implantation ...
C. M. H. Brierley +6 more
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The formation of lipid droplets favors intracellular Mycobacterium leprae survival in SW-10, non-myelinating Schwann cells. [PDF]
PLoS Neglected Tropical Diseases, 2017 Leprosy is a chronic infectious disease that is caused by the obligate intracellular pathogen Mycobacterium leprae (M.leprae), which is the leading cause of all non-traumatic peripheral neuropathies worldwide.
Song-Hyo Jin +2 more
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Schwann-spheres derived from injured peripheral nerves in adult mice--their in vitro characterization and therapeutic potential. [PDF]
PLoS ONE, 2011 Multipotent somatic stem cells have been identified in various adult tissues. However, the stem/progenitor cells of the peripheral nerves have been isolated only from fetal tissues.
Takehiko Takagi +10 more
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Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro
Stem Cells International, 2022 Schwann cells have been found to promote osteogenesis by an unclear molecular mechanism. To better understand how Schwann cells accelerate osteogenesis, RNA-Seq and LC-MS/MS were utilized to explore the transcriptomic and metabolic response of MC3T3-E1 ...
Jun-Qin Li +10 more
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The immunocompetence of Schwann cells [PDF]
Muscle & Nerve, 2007 AbstractSchwann cells are the myelinating glial cells of the peripheral nervous system that support and ensheath axons with myelin to enable rapid saltatory signal propagation in the axon. Immunocompetence, however, has only recently been recognized as an important feature of Schwann cells.
Gerd, Meyer zu Hörste +4 more
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Journal of Experimental & Clinical Cancer Research, 2022 Background Research has indicated that the emergence of Schwann cells around premalignant lesions of colon cancer might be an early indicator promoting the onset of tumorigenesis.
Shengbo Han +13 more
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