Results 11 to 20 of about 106,436 (326)
YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells
Nature Neuroscience, 2016 Yannick Poitelon +16 more
openalex +4 more sources
Neural Regeneration Research, 2023 Studies have shown that human hair keratin (HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secrete nerve growth factor, which ...
Han-Jun Qin +7 more
doaj +1 more source
Ribosomal trafficking is reduced in Schwann cells following induction of myelination. [PDF]
, 2015 Local synthesis of proteins within the Schwann cell periphery is extremely important for efficient process extension and myelination, when cells undergo dramatic changes in polarity and geometry.
Love, James M, Shah, Sameer B
core +5 more sources
FGF5 Regulates Schwann Cell Migration and Adhesion
Frontiers in Cellular Neuroscience, 2020 The fibroblast growth factor (FGF) family polypeptides play key roles in promoting tissue regeneration and repair. FGF5 is strongly up-regulated in Schwann cells of the peripheral nervous system following injury; however, a role for FGF5 in peripheral ...
Bing Chen +7 more
doaj +1 more source
SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination. [PDF]
PLoS ONE, 2014 Schwann cells are an important cell source for regenerative therapy for neural disorders. We investigated the role of the transcription factor sex determining region Y (SRY)-box 10 (SOX10) in the proliferation and myelination of Schwann cells.
Sayaka Fujiwara +9 more
doaj +1 more source
Journal of Nanobiotechnology, 2022 Background Schwann cells, the glial cells in the peripheral nervous system, are highly plastic. In response to nerve injury, Schwann cells are reprogrammed to a series of specialized repair-promoting phenotypes, known as repair Schwann cells, which play ...
Ting Liu, Yang Wang, Laijin Lu, Yi Liu
doaj +1 more source
Hydrogen peroxide is a neuronal alarmin that triggers specific RNAs, local translation of Annexin A2, and cytoskeletal remodeling in Schwann cells [PDF]
, 2018 Schwann cells are key players in neuro-regeneration: They sense "alarm" signals released by degenerating nerve terminals and differentiate toward a proregenerative phenotype, with phagocytosis of nerve debris and nerve guidance.
Duregotti, E +10 more
core +1 more source
Schwann Cell Myelination [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Myelinated nerve fibers are essential for the rapid propagation of action potentials by saltatory conduction. They form as the result of reciprocal interactions between axons and Schwann cells. Extrinsic signals from the axon, and the extracellular matrix, drive Schwann cells to adopt a myelinating fate, whereas myelination reorganizes the axon for its
openaire +2 more sources
Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation. [PDF]
PLoS ONE, 2015 Gliogenesis under pathophysiological conditions is of particular clinical relevance since it may provide evidence for regeneration promoting cells recruitable for therapeutic purposes.
Kristel Kegler +5 more
doaj +1 more source
Embryonic Schwann cell development: the biology of Schwann cell precursors and early Schwann cells
Journal of Anatomy, 1997 The cellular events leading to the generation of Schwann cells from the neural crest have recently been clarified and it is now possible to outline a relatively simple model of the Schwann cell lineage in the rat and mouse. Neural crest cells have to undergo 3 main developmental transitions to become mature Schwann cells.
K R, Jessen, R, Mirsky
openaire +3 more sources