Results 21 to 30 of about 61,604 (256)

Influence of cold-stimulated adipocyte supernatant on the expression of adhesion-related molecules in Schwann cell line

open access: yesBiochemistry and Biophysics Reports, 2023
Bell's palsy is the most common form of facial nerve palsy. This study aimed to explore the pathogenesis of Bell's palsy by investigating the effect of cold-stimulated adipocyte supernatant on adhesion molecule expression in Schwann cell line.
Tiefeng Zhang   +6 more
doaj   +1 more source

The Neurobiology of Schwann Cells

open access: yesBrain Pathology, 1999
This selective review of Schwann cell biology focuses on questions relating to the origins, development and differentiation of Schwann cells and the signals that control these processes. The importance of neuregulins and their receptors in controlling Schwann cell precursor survival and generation of Schwann cells, and the role of these molecules in ...
R, Mirsky, K R, Jessen
openaire   +3 more sources

Heme Oxygenase 1 in Schwann Cells Regulates Peripheral Nerve Degeneration Against Oxidative Stress

open access: yesASN Neuro, 2019
During Wallerian degeneration, Schwann cells lose their characteristic of myelinating axons and shift into the state of developmental promyelinating cells.
Muwoong Kim   +8 more
doaj   +1 more source

Analysis of Schwann Cell Migration and Axon Regeneration Following Nerve Injury in the Sciatic Nerve Bridge

open access: yesFrontiers in Molecular Neuroscience, 2019
While it is proposed that interaction between Schwann cells and axons is key for successful nerve regeneration, the behavior of Schwann cells migrating into a nerve gap following a transection injury and how migrating Schwann cells interact with ...
Bing Chen   +3 more
doaj   +1 more source

Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. [PDF]

open access: yesPLoS ONE, 2010
The myelin sheaths that surround the thick axons of the peripheral nervous system are produced by the highly specialized Schwann cells. Differentiation of Schwann cells and myelination occur in discrete steps.
Juliane Bremer   +5 more
doaj   +1 more source

Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation

open access: yesNeurobiology of Disease, 2010
Schwann cells are the myelinating glia cells of the peripheral nervous system (PNS). In inflammatory neuropathies like the Guillain-Barré syndrome (GBS) Schwann cells become target of an autoimmune response, but may also modulate local inflammation. Here,
Gerd Meyer zu Hörste   +9 more
doaj   +1 more source

TNFα promotes oral cancer growth, pain, and Schwann cell activation

open access: yesScientific Reports, 2021
Oral cancer is very painful and impairs a patient’s ability to eat, talk, and drink. Mediators secreted from oral cancer can excite and sensitize sensory neurons inducing pain.
Elizabeth Salvo   +6 more
doaj   +1 more source

Retracing Schwann Cell Developmental Transitions in Embryonic Dissociated DRG/Schwann Cell Cocultures in Mice

open access: yesFrontiers in Cellular Neuroscience, 2021
Embryonic Dissociated Dorsal Root Ganglia (DRG) cultures are often used to investigate the role of novel molecular pathways or drugs in Schwann cell development and myelination.
Venkat Krishnan Sundaram   +7 more
doaj   +1 more source

Inhibition of Schwann Cell Pyroptosis Promotes Nerve Regeneration in Peripheral Nerve Injury in Rats

open access: yesMediators of Inflammation, 2023
Background. Peripheral nerve injury (PNI) is one of the most debilitating injuries, but therapies for PNI are still far from satisfactory. Pyroptosis, a recently identified form of cell death, has been demonstrated to participate in different diseases ...
Jiayi Wang   +9 more
doaj   +1 more source

Autophagy is involved in the reduction of myelinating Schwann cell cytoplasm during myelin maturation of the peripheral nerve. [PDF]

open access: yesPLoS ONE, 2015
Peripheral nerve myelination involves dynamic changes in Schwann cell morphology and membrane structure. Recent studies have demonstrated that autophagy regulates organelle biogenesis and plasma membrane dynamics.
So Young Jang   +7 more
doaj   +1 more source

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