Angewandte Chemie, EarlyView.The cupula is a membrane within the vestibular organ that senses rotatory accelerations of the head. Metabolic glycoengineering in combination with bioorthogonal labeling demonstrates that in adult zebrafish – being a model for the human inner ear – this membrane is constantly renewed.
Hans Scherer +4 more
wiley +2 more sources
Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice. [PDF]
, 2019 Mounting evidence suggests that antiretroviral therapy (ART) drugs may contribute to the prevalence of HIV-associated neurological dysfunction. The HIV envelope glycoprotein (gp120) is neurotoxic and has been linked to alterations in mitochondrial ...
Achim, Cristian L +11 more
core
The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]
, 1993 Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter +2 more
core +1 more source
Annals of Gastroenterological Surgery, EarlyView.Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara +14 more
wiley +1 more source
Ibrain, EarlyView., 2023 This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju +7 more
wiley +1 more source
Development and consensus process for a clinical pathway for the assessment and management of chemotherapy-induced peripheral neuropathy [PDF]
, 2022 David Mizrahi +9 more
openalex +1 more source
The experiences of people living with peripheral neuropathy in Kuwait - a process map of the patient journey [PDF]
, 2019 Peripheral neuropathy is a neurological disease characterised by pain, numbness, tingling, swelling or muscle weakness due to nerve damage, caused by multiple factors such as trauma, infections and metabolic diseases such as diabetes.
Ben-Tovim, Cozolino, Donna, Harvard
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona +15 more
wiley +1 more source
Impact of foot progression angle modification on plantar loading in individuals with diabetes mellitus and peripheral neuropathy [PDF]
, 2016 AIMS: To determine if participants can reduce foot progression angle (FPA), and if FPA reduction decreases regional plantar stresses and forces in individuals with diabetes.
Bohnert, Kathryn L +5 more
core +2 more sources
Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study [PDF]
, 2018 Purpose In this multicenter study, we evaluated the cumulative burden of morbidity (CBM) among > 1,200 testicular cancer survivors and applied factor analysis to determine the co-occurrence of adverse health outcomes (AHOs).
AnnaLynn M. Williams +20 more
core +1 more source