Results 41 to 50 of about 1,596,501 (294)

Endobronchial ultrasound‐guided versus computed tomography‐guided biopsy for peripheral pulmonary lesions: A meta‐analysis

open access: yesThe Clinical Respiratory Journal, 2021
Background Both endobronchial ultrasound‐guided transbronchial biopsy (EBUS‐TBB) and computed tomography‐guided transthoracic needle biopsy (CT‐TTNB) are approaches commonly utilized to diagnose peripheral pulmonary lesions (PPLs).
Yu‐Fei Fu   +3 more
doaj   +1 more source

Classical supravalvar aortic stenosis and peripheral pulmonary stenosis [PDF]

open access: yes, 2014
Supravalvar aortic stenosis as well as peripheral pulmonary stenosis are rare forms of congenital heart disease, which occur, however, relatively frequently in association.
Ramakrishnan, S.   +3 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Ultrasound Elastography in Evaluation of Peripheral Pulmonary Lesions

open access: yesActa medica Lituanica
Background: Differentiating benign from malignant peripheral pulmonary lesions (PPLs) remains a clinical challenge, especially in resource-limited settings. While computed tomography is the standard imaging modality, it involves radiation exposure and often lacks specificity.
Abdul Rouf   +7 more
openaire   +2 more sources

The peripheral pulmonary lesion - bronchoscopic techniques to improve diagnosis [PDF]

open access: yes, 2020
Lung cancer is a leading cause of cancer-related deaths worldwide. This is no different in Australia where it is the main cause of cancer-related mortality, and the fifth most commonly cancer diagnosed in Australians.
Wong, Michelle Xin Zhi
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

The Value of Combined Radial Endobronchial Ultrasound-Guided Transbronchial Lung Biopsy and Metagenomic Next-Generation Sequencing for Peripheral Pulmonary Infectious Lesions

open access: yesCanadian Respiratory Journal, 2020
Background. Metagenomic next-generation sequencing (mNGS) is a new technology that allows for unbiased detection of pathogens. However, there are few reports on mNGS of lung biopsy tissues for pulmonary infection diagnosis.
Guangsheng Li   +3 more
doaj   +1 more source

Computed Tomography Bronchus Sign Subclassification during Radial Endobronchial Ultrasound-Guided Transbronchial Biopsy: A Retrospective Analysis

open access: yesDiagnostics, 2023
The presence of computed tomography bronchus sign (CT-BS) substantially increases the diagnostic yield of peripheral pulmonary lesions. However, the clinical significance of subdividing CT-BS remains controversial. We classified bronchus types on CT into
Tatsuya Imabayashi   +4 more
doaj   +1 more source

Management of Tetralogy of Fallot with Pulmonary Atresia [PDF]

open access: yes, 2005
Tetralogy of Fallot with Pulmonary Atresia is an extreme form of tetralogy characterized by absence of flow from the right ventricle to the pulmonary arteries.
Prieto, Lourdes R.
core  

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