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Peripheral Mechanisms of Sensitization and Hyperalgesia
1991Classical textbooks of neuroanatomy and neurophysiology discuss pain pathways in a relatively straightforward manner. Thus it is stated that noxious stimuli activate unmyelinated fibers in the periphery. These in turn contact second order neurons in the spinal cord dorsal horn. The latter are cells at the origin of the spinothalamic tract which project
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Peripheral thermal sensitivity in the rabbit
American Journal of Physiology-Legacy Content, 1972M J, Kluger, R R, Gonzalez, J D, Hardy
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NMDARs mediate peripheral and central sensitization contributing to chronic orofacial pain
Frontiers in Cellular Neuroscience, 2022Yanyan Zhang, Jiu Lin, Jie-Fei Shen
exaly
Mechanisms of Peripheral and Central Pain Sensitization: Focus on Ocular Pain
Frontiers in Pharmacology, 2021Giulia Puja +2 more
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Peripheral sensitization of sensory neurons.
Ethnicity & disease, 2010Defining the sites and mechanisms of nociception is an important step in understanding and treating pain. During inflammation, increased nociceptive input from an inflamed organ can sensitize neurons that receive convergent input from an unaffected organ, but the site of visceral cross-sensitivity is unknown.
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