Results 161 to 170 of about 134,700 (260)

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Peripheral T cell lymphoma following CD19-targeted chimeric antigen receptor T cell therapy. [PDF]

Int J Hematol
Tatetsu H, Kato K, Wada A, Hirano T, Ueno S, Miyasato Y, Yamada A, Shichijo T, Higuchi Y, Ueda Y, Nosaka K, Mikami Y, Karube K, Matsuoka M, Yasunaga JI.   +14 more
europepmc   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source

Cooperative role of distinctive TP53 and PTEN combined loss in the peripheral T cell lymphoma-GATA3 molecular subgroup. [PDF]

Sci Adv
Lone WG, Yu J, Liu X, Jochum DT, Bouska A, Shetty K, Herek T, Sharma S, Bi C, Shah R, Nasser ZW, Amador C, Arif A, Mir AR, Li Y, Heavican-Foral TB, Robinson J, Hyde RK, Sakata-Yanagimoto M, Rachagani S, McKeithan TW, Scott DW, Staudt LM, Inghirami G, Feldman A, Greiner T, Vose JM, Rimsza L, Khoury J, Chan WC, Iqbal J, Lymphoma/Leukemia Molecular Profiling Project (LLMPP).   +31 more
europepmc   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Association of PET4 response with outcomes of BV-CHP vs CHOP in the ECHELON-2 trial in CD30+ peripheral T-cell lymphoma. [PDF]

Blood Adv
Iyer S, Mehta-Shah N, Advani R, Bartlett NL, Christensen JH, Morschhauser F, Domingo-Domenech E, Rossi G, Kim WS, Alpdogan O, Feldman TA, Camus V, Gritti G, Zinzani PL, Belada D, Mayer J, Choi I, Cheong JW, Rustia E, Fenton K, Fanale M, Savage KJ, Horwitz SM.   +22 more
europepmc   +1 more source

Breaking through tradition: A new study on the 125I seeds implantation assisted by the puncture angle guidance device

Precision Medical Sciences, EarlyView.
This study showed the puncture angle guide device assisted 125I seeds implantation is safe and feasible. Compared with the manual deployment of needles, the puncture time, the number of puncture needle adjustments, and the number of intraoperative CT scans are significantly reduced, which can be used in clinical applications.
Yufeng Zhang, Yong Feng, Wenjie Guo, Xia He, Lele Zhang, Jiangping Yu, Xiuming Zhang, Wei Qiao   +7 more
wiley   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Nodal peripheral T-cell lymphoma in Finland between 2007 and 2019: Incidence, late morbidity and survival. [PDF]

Br J Haematol
Partanen A, Rönkä A, Anttalainen A, Ukkola-Vuoti L, Toppila I, Kuitunen H, Miettinen T, Kuittinen O.   +7 more
europepmc   +1 more source

A new perspective on radiotherapy in the comprehensive treatment of cancer

Precision Radiation Oncology, EarlyView.
Radiotherapy remains a key component in the comprehensive management of cancer. Its effectiveness is significantly improved through strategic combinations with chemotherapy, targeted therapy, and immunotherapy, providing a range of therapeutic outcomes from cure to palliative care.
Yingze Ma, Hongxuan Yu, Shijie Shang, Shixin Shan, Dawei Chen   +4 more
wiley   +1 more source