Results 121 to 130 of about 313,948 (313)

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

open access: yesAdvanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen   +16 more
wiley   +1 more source

Tumor budding may be a promising prognostic indicator in intrahepatic cholangiocarcinoma: A multicenter retrospective study

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 138-146, January 2023., 2023
High tumor budding is a new candidate for an additional determinant of the T category in staging ICC. An LCSGJ staging system containing an additional evaluation of tumor budding may lead to improved staging accuracy. Abstract Purpose This retrospective study evaluated our hypothesis that high tumor budding (≥10 buds) may help determine the appropriate
Hisashi Kosaka   +9 more
wiley   +1 more source

NETs‐CD44‐IL‐17A Feedback Loop Drives Th17‐Mediated Inflammation in Behçet's Uveitis

open access: yesAdvanced Science, EarlyView.
In experimental autoimmune uveitis (EAU), neutrophils interact with T helper 17 (Th17) cells through neutrophil extracellular traps (NETs) to exert a pro‐inflammatory effect. In vitro and in vivo experiments identify that NETs promote IL‐17A secretion in Th17 cells via CD44, and increasing IL‐17A further induces more NETs formation.
Yi Wu   +11 more
wiley   +1 more source

Prediction of need for bowel resection in acute superior mesenteric artery occlusion: A retrospective study of 48 Japanese patients

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 175-181, January 2023., 2023
In a study of 48 patients with acute superior mesenteric artery occlusion, a logistic regression model using time from onset to diagnosis and the occlusion site of superior mesenteric artery showed 78.6% sensitivity in ruling out cases requiring bowel resection.
Susumu Watada   +9 more
wiley   +1 more source

Perspective in Progress of Cardiovascular Gene Therapy

open access: yesJournal of Pharmacological Sciences, 2004
Recent progress in molecular and cellular biology has developed numerous effective cardiovascular drugs. However, there are still a number of diseases for which no known effective therapy exists, such as peripheral arterial disease, ischemic heart ...
Ryuichi Morishita
doaj  

Assessment of peripheral vascular disease by postocclusive transcutaneous oxygen recovery time [PDF]

open access: bronze, 1984
Harry B. Kram   +3 more
openalex   +1 more source

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

open access: yesAdvanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li   +19 more
wiley   +1 more source

Robust semi-automatic vessel tracing in the human retinal image by an instance segmentation neural network [PDF]

open access: yesarXiv
The morphology and hierarchy of the vascular systems are essential for perfusion in supporting metabolism. In human retina, one of the most energy-demanding organs, retinal circulation nourishes the entire inner retina by an intricate vasculature emerging and remerging at the optic nerve head (ONH). Thus, tracing the vascular branching from ONH through
arxiv  

Nitrotyrosine in peripheral vascular disease [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2003
Da Ros R   +4 more
openaire   +4 more sources

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