The effect of peripheral vascular disease on in-hospital mortality rates with coronary artery bypass surgery [PDF]
John D. Birkmeyer+8 more
openalex +1 more source
Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development
Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He+7 more
wiley +1 more source
The elusive scleral cartilages: Comparative anatomy and development in teleosts and avians
Abstract The sclera of all vertebrate eyes is comprised of connective tissue, with some organisms developing cartilage within this tissue. A review of the cartilages that have been described in the vertebrate sclera and their anatomical relationships is discussed together with their potential homology.
Tamara A. Franz‐Odendaal
wiley +1 more source
Prevalence of angiographic atherosclerotic renal artery disease and its relationship to the anatomical extent of peripheral vascular atherosclerosis [PDF]
Wendy Metcalfe, Alan Reid, Colin Geddes
openalex +1 more source
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang+5 more
wiley +1 more source
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao+16 more
wiley +1 more source
Cross-sectional study of lipoprotein(a) and the severity of coronary artery disease, cerebrovascular disease, and peripheral vascular disease in a group of South Asian patients. [PDF]
Athauda-Arachchi PM+12 more
europepmc +1 more source
Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang+8 more
wiley +1 more source
PROGRESSIVE VS. SINGLE-INTENSITY TREADMILL TESTS WITH PERIPHERAL VASCULAR OCCLUSIVE DISEASE
B. W. Cantwell+5 more
openalex +1 more source
Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng+10 more
wiley +1 more source