Results 191 to 200 of about 313,948 (313)

Basic biology and roles of CEBPD in cardiovascular disease. [PDF]

Cell Death Discov
Li T, Lin S, Zhu Y, Ye D, Rong X, Wang L.   +5 more
europepmc   +1 more source

Novel prostaglandin therapy using a lipid microsphere in peripheral vascular disease

, 1984
星 恵子, 柳川 明, 水島 裕
openalex   +2 more sources

Prevalence and risk factors of peripheral vascular disease in a selected South Indian population: the Chennai Urban Population Study. [PDF]

, 2000
G. Premalatha, S Shanthirani, R Deepa, Jerome H. Markovitz, Viswanathan Mohan   +4 more
openalex   +1 more source

Bioengineering Platelets Presenting PD‐L1, Galectin‐9 and BTLA to Ameliorate Type 1 Diabetes

Advanced Science, EarlyView.
IFN‐γ‐primed platelets enriched with immunosuppressive ligands (PD‐L1, PD‐L2, BTLA, and Gal‐9) are shown to induce T cell exhaustion and apoptosis, preserving β‐cell function and preventing hyperglycemia progression in type 1 diabetes. IFN‐γ platelets also promote Treg expansion, macrophage polarization, and β‐cell proliferation, offering a promising ...
Yumeng Ma, Fanqiang Meng, Zhongda Lin, Yanjun Chen, Tianyu Lan, Zhaoxin Yang, Rui Diao, Xiaozhou Zhang, Qi Chen, Chi Zhang, Yishi Tian, Chanjuan Li, Wenli Fang, Xin Liang, Xudong Zhang   +14 more
wiley   +1 more source

Flexible Optoelectronic Hybrid Microfiber Long‐period Grating Multimodal Sensor

Advanced Science, EarlyView.
An entirely new optoelectronic hybrid multimodal optical fiber sensor which can simultaneously monitor biomechanics and glucose is demonstrated. The developed method simultaneously integrates two heterogeneous sensing mechanisms, optical and electrical, into a single sensor in a compact manner. Optical and electrical sensors can work simultaneously but
Zhenru Li, Li‐Peng Sun, Yanzhen Tan, Zhiwei Wang, Xiao Yang, Tiansheng Huang, Jie Li, Yi Zhang, Bai‐Ou Guan   +8 more
wiley   +1 more source

Editorial: Lipid metabolism dysregulation in obesity-related diseases and neurodegeneration. [PDF]

Front Endocrinol (Lausanne)
Zeng J, Lo CH.
europepmc   +1 more source

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

A simplified in vitro disease-mimicking culture system can determine the angiogenic effect of medicines on vascular diseases. [PDF]

Cytotechnology
Moon S, Ito Y.
europepmc   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source