Results 211 to 220 of about 1,189,699 (374)

Coronary artery disease is highly prevalent among patients with premature peripheral vascular disease [PDF]

open access: bronze, 1994
Rudy J. Valentine   +4 more
openalex   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

open access: yesAdvanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi   +5 more
wiley   +1 more source

Cytokine Engineering Approaches for Regenerative Medicine

open access: yesAdvanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Asymptomatic carotid artery stenosis in patients with severe peripheral vascular diseases

open access: yesJournal of Research in Medical Sciences, 2009
<ul><li><strong>BACKGROUND</strong>: The prevalence of carotid artery stenosis (CAS) in the&nbsp; eneral population is not high enough to justify screening programs.
Rasoul Mirsharifi   +3 more
doaj  

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

open access: yesAdvanced Therapeutics, EarlyView.
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer   +9 more
wiley   +1 more source

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