Results 81 to 90 of about 1,283,588 (394)

The Vascular Endothelium and Human Diseases

open access: yesInternational Journal on Biological Sciences, 2013
Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key function of participating in the maintenance of patent and ...
P. Rajendran   +6 more
semanticscholar   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam   +6 more
wiley   +1 more source

Hematoporphyrin photodynamic therapy for treatment of pathological scar with ulceration: A case report

open access: yesPhotodiagnosis and Photodynamic Therapy
Pathological scars result from abnormal wound healing and represent a fibrotic process in the repair of skin injuries. Post-burn scars are prone to malignant transformation, especially when ulceration occurs, raising concerns for precancerous lesions. We
Lianheng Xia   +7 more
doaj   +1 more source

Comorbid conditions responsible for the higher complications and poorer outcome in cardiac and vascular surgery: Time to reconsider hyperhomocysteinemia and its repercussions

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2019
Background: Plasma homocysteine is a perceived risk factor for the cardiovascular diseases. Many studies confirmed its remarkably high level with severity of the disease.
Arun Kumar Haridas   +1 more
doaj   +1 more source

Selenium and vascular health [PDF]

open access: yes, 2011
Peer reviewedPublisher ...
Sneddon, Alan A.
core   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu   +9 more
wiley   +1 more source

Global Impact of Peripheral Obstructive Arterial Disease in Portugal: An Eight Year Study

open access: yesActa Médica Portuguesa, 2019
Introduction: Peripheral arterial disease has an important impact on morbidity/mortality. The objective of this study was to quantify the impact of this disease in Portugal during the last eight years, expressed by the volume of admissions, treatment ...
Mariana Moutinho   +6 more
doaj   +1 more source

Оптимизация учебной программы по физическому воспитанию студентов, имеющих отклонения со стороны здоровья. [PDF]

open access: yes, 2018
The purpose of research - to identify ways to optimize the physical education curriculum for students with poor health, with diseases of the cardio-vascular system.To achieve the goal, we used the following methods: analysis of scientific and ...
Biletska, Viktoriia   +2 more
core  

The multifaceted roles of PI3Kγ in hypertension, vascular biology, and inflammation [PDF]

open access: yes, 2016
PI3Kγ is a multifaceted protein, crucially involved in cardiovascular and immune systems. Several studies described the biological and physiological functions of this enzyme in the regulation of cardiovascular system, while others stressed its role in ...
Carnevale, Daniela   +2 more
core   +2 more sources

Time Trends and Predictors of Gout Remission Over 6 Years

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah   +5 more
wiley   +1 more source

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