Results 61 to 70 of about 81,887 (264)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Twin subgraphs and core-semiperiphery-periphery structures
, 2018 A standard approach to reduce the complexity of very large networks is to group together sets of nodes into clusters according to some criterion which reflects certain structural properties of the network.
Riaza, Ricardo
core +3 more sources
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
THE WEB IS THE LIMIT: LANGUAGE, CULTURE AND MOOCS [PDF]
Diversitate si Identitate Culturala in Europa, 2014 MOOCs remain the buzzwords of the current landscape of higher education (HE) provision. In the context of the ever growing use of technology through e - Learning and OpenCourseWare and of the new generation of tablet - toting, hyper - connected youth ...
Silvia FLOREA +2 more
doaj
Проект Байкал, 2017 Capitals gather constellations of bright and creative people, attracting them from the peripheries. Tchekhov’s sisters were anxious to get to Moscow, d’Artagnan – to Paris.
Elena Grigoryeva, Konstantin Lidin
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
State, market and administration of territories in the city of Rio de Janeiro
Vibrant: Virtual Brazilian Anthropology, 2017 This article discusses the new modality of governance of the poor in border territories of Brazilian cities, specifically in their favelas and peripheries. We analyze, based on research carried out in Rio de Janeiro, dynamics that, at first glance, could
Márcia Pereira Leite
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source