Results 81 to 90 of about 81,887 (264)
Revista CIDOB d'Afers InternacionalsThe rise and deployment of artificial intelligence (AI) is having an exponential impact on the process of transformation and realignment of global geopolitics. While the United States, China and to a lesser extent the European Union (EU) are leading the “
Carme Colomina Saló +1 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Samba Rock Culture in São Paulo: Beyond the Dance [PDF]
, 2013 Latin American ...
Kateneva, Krista
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Social and ethnic segregation amongst the smallest Hungarian villages [PDF]
Geographica Pannonica, 2018 Social segregation is one of the most important social problems in Central-Eastern Europe not only in urban, but also rural areas. The social segregation usually coexists with ethnic segregation.
Balogh András +2 more
doaj
Cryogenic apparatus for measuring the intensity of magnetic fields [PDF]
, 1969 Cryogenic flux-gated magnetometer using ...
Dimeff, J.
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Religião e SociedadeResumo: O artigo aborda o trânsito efetuado por jovens moradores das periferias que, negociando entre províncias de significados de aparência antagônica, circulam entre o suposto hedonismo da cultura funk e o aparente ascetismo pentecostal.
Réia Silvia Gonçalves Pereira
doaj +1 more source