Results 91 to 100 of about 21,267 (307)

Connections. Collaborative Imaginaries of Territories in Change across Europe

open access: yesRevue Européenne des Migrations Internationales, 2023
Melissa Moralli
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Social and ethnic segregation amongst the smallest Hungarian villages [PDF]

open access: yesGeographica Pannonica, 2018
Social segregation is one of the most important social problems in Central-Eastern Europe not only in urban, but also rural areas. The social segregation usually coexists with ethnic segregation.
Balogh András   +2 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Introduction: Revisiting centres and peripheries in Iberian studies: Culture, history and socio-economic change

open access: yes, 2019
Introduction to edited book.The centres and peripheries that form the focus of the book are markedly diverse and interdisciplinary in nature. In terms of geography these range from considerations of transnational influences in the wider Hispanic and ...
Gant, Mark
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Poetic Peripheries

open access: yes, 2019
The Poetic Peripheries exhibition (Vivienne Crisp Gallery) includes artists Taina Kontio, Satu Miettinen, Mari Mäkiranta and Melanie Sarantou. This collective includes four researcher-artists who focus on the questions of social responsibility, arctic ...
Mäkiranta, Mari; id_orcid   +3 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

PERIFACONNECTION: SHARING PROTAGONISMS

open access: yesSur: International Journal on Human Rights, 2020
Through the PerifaConnection network, five young, black Brazilians raise their voice to defend rights and reclaim the power of the territory of the periphery.
Raull Santiago   +4 more
doaj  

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