Results 101 to 110 of about 21,267 (307)
Urban Transformations: Centres, Peripheries and Systems
, 2019 Book review by Maxwell Hartt of Urban Transformations: Centres, Peripheries and Systems, Daniel P.
Hartt, Maxwell
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
‘Inner peripheries’ and infrastructural policies in Italy
, 2020 The paper is related to the Italian National Research Council’s project “Territorial Impact Assessment of the Territorial Cohesion in the Italian regions.
Pagetti Flora
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Arab Spring: The Role of the Peripheries
, 2015 The emerging literature on the so-called ‘Arab Spring’ has largely focused on the evolution of the uprisings in cities and power centres. In order to reach a more diversified and in-depth understanding of the ‘Arab Spring’, this article examines how ...
Daniela Huber +5 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Reconfiguring EU Peripheries explores the diverse nature of the European Union’s interactions with its peripheries. Focusing on a period of rising regional tensions marked most recently by the war in Ukraine, the volume casts new empirical and conceptual
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Contentious colonies: The positional power of imperial peripheries [Elektronisk resurs]
, 2020 While structural models of empire have recently re-emerged in the theoretical debates in the field of International Relations, a lack of attention has been paid to peripheral actors therein.
Gade Viksand, Sindre,, Lund University.
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source