Results 101 to 110 of about 1,030,006 (350)
Socio-economic changes in the borderlands of the Visegrad Group (V4) countries
Under the influence of globalization and state integration processes, the importance of a border as a barrier is gradually decreasing. Borderlands are still perceived as specific phenomena, however, not only in terms of historical development but ...
Máliková Lucia +3 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
This paper aims to study the ambiguous relationship between the European Union and the countries of the Western Balkans which are waiting for their accession.
Emmanuelle Chaveneau, Amaël Cattaruzza
doaj +1 more source
Kurkowska-Budzan, Marta +2 more
openaire +2 more sources
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
From the Periphery to the Deep End: A Critique of Joshua Maponga’s Religio-Cultural Pedagogy [PDF]
A plethora of discourses have emerged on the religio-cultural pedagogy of Joshua Maponga, a Zimbabwean clergy. Maponga’s religious and cultural pedagogy has been oscillating from the periphery to the deep end.
Peter Masvotore, Martin Mujinga
doaj +1 more source
Monetary Policy and Regional Interest Rates in the United States, 1880-2002 [PDF]
The long running debate among economic historians over how long it took regional financial markets in the United States to become fully integrated should be of considerable interest to students of monetary unions. This paper reviews the debate, discusses
Hugh Rockoff, John Landon-Lane
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Composition of the nuclear periphery from antiproton absorption
Thirteen targets with mass numbers from 58 to 238 were irradiated with the antiproton beam from the Low Energy Antiproton Ring facility at CERN leading to the formation of antiprotonic atoms of these heavy elements.
Hartmann, F. J. +8 more
core +1 more source

