Results 131 to 140 of about 1,205,038 (394)
Kurkowska-Budzan, Marta +2 more
openaire +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Utopian semiospheres: Isolation and dialogue across borders
The paper applies Juri Lotman’s theory of the semiosphere to utopian studies with the aim of identifying the principal components and mode of functioning of classic utopian discourse.
Artur Blaim, Ludmiła Gruszewska-Blaim
doaj +1 more source
This paper aims to study the ambiguous relationship between the European Union and the countries of the Western Balkans which are waiting for their accession.
Emmanuelle Chaveneau, Amaël Cattaruzza
doaj +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
From the Periphery to the Deep End: A Critique of Joshua Maponga’s Religio-Cultural Pedagogy [PDF]
A plethora of discourses have emerged on the religio-cultural pedagogy of Joshua Maponga, a Zimbabwean clergy. Maponga’s religious and cultural pedagogy has been oscillating from the periphery to the deep end.
Peter Masvotore, Martin Mujinga
doaj +1 more source
Core-periphery analysis: a tale of two nations [PDF]
Bias, unreliability and omission have been documented in traditional sources of trade data; the lack of service data in trade statistics is the most frequently cited shortcoming. Current trade liberalization is likely to exacerbate these deficiencies.
Jacobson, David, Mack, Richard S.
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
A viral lncRNA tethers HSV-1 genomes at the nuclear periphery to establish viral latency [PDF]
Tristan R. Grams +2 more
openalex +1 more source
Paramagnetic Reentrance Effect in NS Proximity Cylinders
A scenario for the unusual paramagnetic reentrance behavior at ultra-low temperatures in Nb-Ag, Nb-Au, and Nb-Cu cylinders is presented. For the diamagnetic response down to temperatures of the order 15 mK, the standard theory (quasi-classical ...
Belzig +13 more
core +1 more source

